Riboflavin (b2) is a complete no-brainer. 0 side effects and dirt cheap.
Especially if your second and third toes any toenails are full of fungus/athletes foot.
The Chinese believe that your second and third toe is a place where toxins leave the body. The Chinese believe PD is “stuck” in fight or flight.
My Parkinson’s is only on my right side. Coincidentally, my right foot toenails second and third toes were full of athletes foot. My left side was free from Parkinson’s and gross toenails. I started restore gold, which has many antioxidant supplements, shortly after being diagnosed. With the restore gold, I did not progress but for some dumb idea I stopped taking it for about six months after 3 or so years of taking it. In those six months I had a neurologist appointment, and my neurologist said that my Parkinson’s was moving to my left side. Coincidentally my second and third toenails on my left side were starting cloud up. I restarted the restore gold and my toenails cleared up and my neurologist said that there was no Parkinson’s in my left side anymore. Restore gold was the only difference.
About a year ago, I had a blood test showing I had almost no riboflavin in my body. I started supplementing riboflavin every 8 hrs. My toenails on my Parkinson side are now clear. They haven’t been clear for at least five years before being diagnosed. I’m back to my starting dose of levodopa. The real change other than the riboflavin is the Sauna/cold plunge/ Wim Hof/ fasting.
I copied and pasted some important information that I’ve written previously about B2 /MTHFR.
I believe a low b2 levels caused a ton of my issues. B2 help lower homocysteine that is correlated with PD. Most of all, MTHFR which is said to be a b2 deficiency. MTHFR struggles with removing toxins. They cannot convert folic acid to folate. It actually blocks the pathway. This is VITAL!!! Your folate levels will show fine but it’s not working well.Your most likely borderline anemic. Folate and B12 is vital for the production of blood. I was borderline anemic for many years. The ranges of blood test are not precise enough. (MCV 99 no anemia /MCV100 anemia) Who came up with the range?? Blood is key in most health. Long term low blood to the brain??? Diet soda, high carb, low nutrients food. MTHFR cannot process synthetic vitamins. These synthetic vitamins are harmful. In the late 90’s, the FDA decided to enrich flour with synthetic vitamins. This is causing huge problems. 30-40% of the population have a form of MTHFR. Unintended consequences.
This has pretty easy solutions. B2 is the single most important vitamin for me. 0 side effects. Everyone with Parkinson needs to supplement with this. It’s non-toxic, no side effects and dirt cheap. They actually had a study Treated PD patients with just b2 and removed red meat. They had amazing results. Modern medicine has completely discounted it for 20 years.
Modern medicine is beginning to figure out there is something related to low riboflavin and neurological degeneration.
Really you have nothing to lose. It took me a long time to notice the results, but really the only side effect was dark, yellow urine. You’re probably not gonna notice because the changes will be so gradual. Just start taking it, you’ll thank me later.
I've made an overview of any low-dose B complexes and multivitamins. There are also categories of non-synthetis B vitamins, with minimum dosages from 1,4 mg, 100% of the daily requirement.
Hello 38 . Thanks for suggestion. I've taken B Complex on and off since my interest in supplements in my 20's . I'm now 66 ! I managed to single out Riboflavin when in my 40's when using it for migraine prophylaxis. A bit of research showed that it can be a bladder irritant in some individuals, of which, unfortunately I'm one . Because of that I cannot take B Complex. I have to buy the B's singly, and just take B2 occasionally. So l've not seen anyone with the same problem.
This is so interesting. I don't have PD, my husband does but I take a lot of the supplements I give him of which B Complex was one but I worked out a correlation between taking it and having a bit of bladder irritation but didn't realise this is something that's been documented.I also have toe nail fungus on one big toe and the 4th toe but this is due to injury and then the fungus appeared which I've been trying to get rid of using tea tree oil and various 'paint on' applications, so far without success.
Vitamin B2 / Riboflavin is an antimicrobial which means it kills fungus too, which imo is important in PD and many other health conditions! Here is a relevant link :
' Aside from being critically important for maintaining human health, recent evidence reported that riboflavin can suppress or inactivate the growth of different microbes including bacteria, viruses, fungi and parasites, suggesting the possible role of riboflavin as an antimicrobial agent (Akompong et al., 2000; Kashiwabuchi et al.,2013; Keil et al., 2013; Tonnetti et al., 2013; Ahgilan et al., 2016;). '
The change in urine color and smell may be a little off putting for some though.
Any contraindications for B2 supplementation if also planning to start High dose B1? Would start B2 first and wait on B1 a bit to not confuse the effects.
He also gets 18mg per day from his Hardys multinutrient.
He tried another one (solgar) when it ran out but over that period he didn’t feel as good. Now he is on this one again he feels better again. But that might just be a coincidence as time of year affects him too with spring pollens.
He has a toenail fungal infection too on his left side, but it is his right side which doesn’t work as well. (His dominant side).
1 multivitamin pill is usually sufficient for PWP. If your husband only takes Hardys, it already exceed the recommended daily intake of vitamin B2 by 1386%.
Considering the low absorption of B2 supplementation, the overall additional increase in the B2 value in the body would be approximately 100% with Hardys, ensuring more than enough intake.
And yet when he takes it he feels better than when he doesn’t take it.
Maybe in the water sipped over the day it means it is always available to the right position in his gut but in a capsule it is delivered further down in a lump and washes out in the next drink. Who knows why things work. Maybe the yellow drink pychologically makes him feel better although the other brand didn’t.
This is from their blurb
“Taking B vitamins already in their coenzymated forms allows the body to use them directly. Thus, the amount that is needed by the body is less in order to achieve the same benefits. BioCoenzymated takes it one step further. Using our proprietary EnviroSimplex® technology, we've created a unique BioCoenzymated process using organic, farm fresh plant extracts from whole food sources and the coenzyme form of B vitamins. The synergy between the phytochemicals found in these plant extracts and the coenzyme B vitamin optimizes absorption.
The results?
BioCoenzymated delivers the most metabolically active nutrients to your cells to utilize most effectively.”
Perhaps their proprietary blend works better for him.
I think people have different gene SNPs which means some people don’t utilise vitamins as well as others. For example the mthfr defect which means synthetic B vitamins folic acid and cyanocobalamin that most people can break into their natural forms can’t be broken down by some people. He has a double of this snp.
The research probably uses a mixture of people so most probably don’t have the faulty gene SNPs.
His genetic report says he needs a lot of B2 s to make up for the fact he doesn’t utilise it well. Some other snp of his is faulty. This might be the reason the solgar one didn’t work on him.
His d vitamin processing also is faulty.
Ironically the people that need to be taking a supplement are probably people with faulty SNPs . So they should just test things on them. No one else would need more if they can get it from food easily.
That depends on the dosage of your vitamin B2 as a standalone supplement, but also in your B-complex (or multivitamin), and of course, how much you want to increase your B2 level.
You may be right, I don’t know about an imbalance, but since I added it. My life has changed for the better . I believe most b vitamins don’t need to supplemented if you have a good diet. I think if I were u, I’d do a blood test after starting riboflavin to check for deficiency. You may not be deficient in b2, but similar to be b1 therapy, maybe PD patients need more than the blood tests ranges imply. Who came up with the ranges. In Japan, any b12 levels under 600, they supplement. In the united states it can be as low as 180. People have been in full blow dementia in the 400’s. I believe there are a percentage of lots of neurological diseases that are just b12 deficiency’s.
I look at it this way, if there’s no toxicity, no harm, nothing to lose, why not give it a shot. Remember, it takes a long time to see any effect, multiple months.
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Digging Deeper into Neuron Valley
