Is High Dose Thiamine (HDT) a mechanism of repairing a Leaky Brain? And, a reason HDT works.

[Gcf51]

Is High Dose Thiamine (HDT) a mechanism of repairing a Leaky Brain? And, a reason HDT works.

…Several B vitamins sup.port the health of the blood-brain barrier:

Vitamin B1 (thiamine) deficiency disrupts the blood-brain barrier and supplementation can restore it.

Vitamins B12, B5, and B9 (folate) can restore blood-brain barrier integrity.

thefnc.com/research/nutrien....

[Esperanto]

The article does not specifically recommend the use of HDT, but it does suggest balancing blood sugar levels, avoiding inflammatory foods and chemicals, and following a nutritious diet to restore the blood-brain barrier. It also emphasizes the importance of certain nutrients, such as resveratrol, curcumin, sulforaphane, vitamin D3, B-vitamins (B1, B5, B9, B12), magnesium, and omega-3 fatty acids.

Considering the common deficiencies of certain nutrients in PD, you would therefore think of following the MIND or Mediterranean diet, and possibly supplementing with a low-dose vitamin B complex (also considering the importance of B2, B3, and B6), vitamin D3, and magnesium.

[Boscoejean]

"Thiamine deficiency impairs the integrity of the blood-brain barrier, thereby enabling iron to pass through and accumulate in the brain."

alz-journals.onlinelibrary....

[Gcf51 in reply to Boscoejean]

I will emphasis Deficiency.....