Proved today that HDT ( high dose thiamine ) improves all my symptoms .And now I can't get it. Any ideas?

[Celtis]

I have had a really bad month,tremor much worse, dropping cups. balance too, falling all over the place when I walk, immense tiredness, brain fog, unable to read a story aloud because I am too slow to read ahead so as to read with proper emphasis, tears because I felt that this was dementia gripping me. And worst of all a kind of blank despair, a giving up. I couldn't gather energy enough to care.

And then my husband suggested that I go back to the dose of HDT which made so much difference before. I have been cutting back because I know there is a shortage in South Africa and I have am afraid of being without it.

So I did that and hallelujah! All the difficulties seemed to melt away. I had energy again, walked nearly easily and further, found I could read better. But most of all, the depression had lifted. The world was beautiful again. I felt hopeful. It was worth trying.

BUT I can't get thiamine hcl any where. Amazon won't deliver to South Africa and I believe there is none in the country.. Could thiamine nitrate do instead? Can anyone advise me?

[Hidden]

An Italian pharmacy will supply. It is listed in the group:

Vitamin B1 use instructions ;

Join Facebook group Parkinson’s thiamine hcl

m.facebook.com/groups/23226...

[Hidden]

From Announcement section of group:

One additional source of B1, thiamine hcl capsules:

You can try to use a preparation of vitamin b1 pure, without any excipient in case the patient is not allergic to thiamine but to the substances that are used to compact it in the capsules or tablets. To us in Italy provides the pharmacy Severi of Grosseto that assured me that can ship it worldwide and I assure you at good prices. Contact them directly for information from them on their pure thiamine. Below is the email address.

The following is direct from the pharmacy to Dr. Costantini :

Dear Antonio, I'm going to give you the following words in English that you requested for your Anglo-Saxon patients: "Our Pharmacy prepares capsules of Vitamin B1 (Thiamine) in the prescribed dosages.The preparations is carried out with exclusively pure Thiamine (100%) without any added excipient. For more information, write an email to: [e-mail] "If you think you need to add something, just let me know. Cordiali salutiAndrea Severi

[Celtis in reply to Hidden]

Many thanks for that.I have just been contacted by someone who can do thiamine nitrate. What is your opinion about that.

[park_bear in reply to Celtis]

If it is possible for you to get thiamine HCL I would definitely opt for that. Here are the results of my checking into thiamine mononitrate:

I searched for "Thiamine mononitrate toxicity" and came up empty. According to this document: sennutricion.org/media/Docs...

thiamine in general is extremely well tolerated.

Doctor Costantini apparently said that thiamine mononitrate can cause headaches. On this site the following things have been said about thiamine mononitrate but I did not find confirmation in the literature:

• Can cause kidney stones

• Bioaccumulates in fat

• "Does not work"

Apparently it can cause allergic reactions: "1000 mg of thiamine mononitrate once a day. I had to stop taking this medication because it caused ... a severe rash."

[Celtis in reply to park_bear]

Thank you for such a detailed response. It is reassuring just to know that I might be able to try the mononitrate for a short time probably without risking much , just until I can organise some other source. I really don't want to be without it.

[Hidden in reply to Celtis]

Ditto Park_Bear

[SilentEchoes in reply to Hidden]

You're a gem

[Celtis in reply to Hidden]

Thank

[cshamb]

How much do u take?

[Celtis in reply to cshamb]

The dose that made so much difference was 2x300mg morning and 1x300mg afternoon. I am Caucasian, a woman and I weigh 48kgs. I have been taking about 5 mg in powder form twice a day, so this was a big jump.

[KERRINGTON in reply to Celtis]

Could you clarify the am dose for me ? Did you take 1 300mg dose am, then a few hours later take the 2nd am dose ? Thanks

[Celtis in reply to KERRINGTON]

I took 2x300mg tablets together in the morning and1x300mg in the afternoon. Everyone is different I think, but that worked for me.

[cshamb in reply to Celtis]

Thanks for your reply. I started again with B1, 500g 2x daily. Does it depend on your weight on how much to take?

[Celtis in reply to cshamb]

I think your weight is important. I weigh 48kg

[Gioc]

The thaimin hcl is a very common product and costs little is unreal that it is not available, there are also substitutes that others will soon recommend you. It is also used a lot in oenology for brewing. I also take it in the pharmacy under the name BENERVA@.

[Celtis in reply to Gioc]

We have had no.alcohol and no.cigarette sales for 5 weeks of lockdown. And no prospect of that changing.

If t can be used in brewing I guess no wonder there is none in the country!

Thanks for your reply.

[Gioc in reply to Celtis]

Ha ha,

I was just saying that to defuse.

But in case of famine, you could always go to the nearest brewery and buy some.

vason.com/index.cfm/it/prod...

I like being original .

[Hidden]

its best as a sub-q injection....i have a friend who does that he gets it from his dr in canada. cheers.

[SilentEchoes in reply to Hidden]

I get my from Tractor Supply

durvet.com/product/high-lev...

[Celtis in reply to SilentEchoes]

Thank you

[bepo in reply to SilentEchoes]

Amazing!

[SilentEchoes in reply to bepo]

I know my way around a farm store 💕

[Juliegrace in reply to Hidden]

The injection that is recommended is IM, intramuscular, not subcutaneous.

[Hidden in reply to Juliegrace]

i only know my friend uses it sub q. i cant speak to anything else. cheers.

[Enidah]

What about Vitacost? I checked the website few days ago and they had the capsules 500mg.

[Celtis in reply to Enidah]

Thanks. I checked that and found many that will deliver here.l

[LAJ12345]

Have you tried vitacost and purebulk?

bulksupplements.com/product... this pure powder not capsules but they have it

[Oceanflow in reply to LAJ12345]

How do you take the powder form? Mixed into coffee?

[chartist]

This place says they ship to South Africa. I found this 100 mg thiamin hydrochloride. That was the first product I found, but you can probably find others on their site.

evitamins.com/za/vitamin-b-...

Art

[Celtis in reply to chartist]

Thank you Art, always there to answer our questions.

[bepo in reply to chartist]

George is taking Solgar thiamine without the HCL. Can it make that much difference.? We also have liquid HCL. Maybe he could take a drop of that in his water with the B1?

[chartist in reply to bepo]

If it is this one

vitacost.com/solgar-vitamin...

it is thiamine hydrochloride, which would be what Dr. Costantini always recommended.

Art

[bepo in reply to chartist]

Yes he is taking Solgar B1. Thank you.

[Buckholt]

Try this UK supplier. Looks like they ship worldwide .

gandgvitamins.com/vitamin-b...

[Giovi1960]

I just got it from luckyvitamin.com

[TsaarPeter]

Did you try I Herb?

[MarionP]

If "A" works, then only get "A" Don't mess with other things unless you absolutely cannot find any other choice. This is no time to learn the hard way about chemistry and experimentation and complicating things. Right now we would say you are in emergency status and you don't have time to futz around until you cannot get a supply of the exact right thing, which is B1 hcl.

There has to be somebody besides Amazon who can do shipping, especially out of Europe. But that is something you discuss with the seller who should be able to figure that out, who is best and fastest.

Then make 3 separate orders: a 2 decent sized orders and 1 separate massive order. The decent size orders arrive fastest and because they are not massive can be filled and sent quickest to you. Then the massive order is separately filled and supply delays don't impede the first two decent sized orders.

Then a 4th order: autoship.

[20fatcats]

Hi. Im so sorry to hear you cant get it. It is very upsetting I know to find something and then have to out of reach. In new Zealand I was on injections for a while. I found a compounding pharmacy that made it up for me with a doctors prescription. It was more expensive than tablets though and then I had to get the doctors nurse to inject me twice a week.

[Routine100]

il.pipingrock.com/?rwcode=E... I buy B-1 from this company 100 MG