mannitol?

[Sandmanliz]

I was wondering if anyone could update me on their use of mannitol? I hear it helps with fatigue? thanks!

[CaseyInsights]

For fatigue, Niacin worked like a charm for my spouse. She has been using 500mg controlled release for over a year and a half.

Here is an into article to this nutrient -

drlamcoaching.com/adrenal-f...

P.S: Niacin is an NAD+ precursor - a key molecule in making ATP the energy molecule that fuel cells.

One other precursor is Nicotinamide mononucleotide (NMN).

Another NAD+ precursor is nicotinamide riboside (NR).

[CaseyInsights]

…and here is a Parkinson specific study, that addresses both the fatigue problem and the motor problems

Low-Dose Niacin Supplementation Improves Motor Function in US Veterans with Parkinson’s Disease

ncbi.nlm.nih.gov/pmc/articl...

Excerpt:

We have previously shown that niacin and NAD levels in PD patients are decreased compared to age-matched controls. Fatigue, depression, strength, sleep, and quality of life indicators may be affected by the reduction in niacin levels. In this study, six months or one year of niacin reduced typical PD motor symptoms and fatigue and stabilized serotonin levels and REM sleep percentage. These effects are highly beneficial for the PD patient’s quality of life. Many PD patients complain of both depression and fatigue. This study showed a halting or slowing of the drop in serotonin levels by niacin, which could potentially reduce depression or improve mood. Additionally, fatigue is likely enhanced by increasing NAD, which is low in aging populations and even lower in PD. 

[gwendolinej]

it certainly worked for my husband. See my post.

Gwendoline