Vaccine

[quiz0019]

view.michaeljfox-email.org/...

[Bolt_Upright]

The Latest in Efforts to Develop a Vaccine against Parkinson’s michaeljfox.org/news/latest...

"The in-person study enrolled 50 eligible, participants without PD who received three rounds of the vaccine or placebo injections at weeks one, five and 13. Of the 50 participants, 23 received all 3 doses and concluded that the vaccine was generally safe, well tolerated and induced anti-alpha-synuclein antibodies."

I worry about those healthy subjects that now have anti-alpha-synuclein antibodies in their system.

[park_bear in reply to Bolt_Upright]

movementdisorders.onlinelib...

"The vaccine candidate UB-312 was selected for its ability to induce antibodies targeting specifically the pathological forms of αSyn. In preclinical studies, UB-312 demonstrated high immunogenicity across species (unpublished data). Antibodies induced after UB-312 immunization in guinea pigs were shown to selectively target oligomeric and fibrillar forms of αSyn, while showing little or no binding to monomeric αSyn."

[Gcf51]

Will be interesting to see if those 23 Human Giana Pigs with antibodies:

1) Develop any side efforts. (I have read and as I understand--αSyn serves a function and it is the misfolded αSyn that cause the problem.)

2) Will the Vaccine stop the misfolding. (Will we have to wait till they die to dissect their brains to see.)

3) The study doesn't say any of the 23 had Parkinson or markers for increased risk of PD.

I am guilty of not reading the whole study.

It was a safety study and not designed to see if it really works.

As Bolt says, "I worry about those healthy subjects that now have anti-alpha-synuclein antibodies in their system."

[Rupa88]

useless studies

Your donation in action

Yeah

Your donation in our pockets and penny of it goes to do non sense studies

60 years and nothing

Read the detailed story of Doc versus Parkinson and see how crooked the FDA and our health system is

[Solvang53]

sadly the MJF foundation is an arm of big pharma...pushing their useless drugs and now vaccines...NO VACCINES are safe or effective...do your own research and dont fall for the scam

[kaypeeoh]

I understand that people who died of PD were autopsied and lesions were found in the substantia nigra. Under the microscope the lesions were were found to be alpha synucleon. So alpha synucleon is the causative agent? Then antibodies to alpha synucleon could be curative?

I was dx'd with MS long before the PD dx. The treatment was Tysabri, a monoclonal antibody. MS is thought to produce abnormal monocytes that can cross the BBB and attack myelin. Tysabri attacks those abby monos. But what is alpha synucleon doing? It hangs around long enough to mis-fold. Perhaps antibodies can clear it out?

For other reasons I tried AHT: Autohemotherapy. I had developed a DVT: Deep Vein Thrombosis. A blood clot that medication wasn't removing. As an experiment I tried AHT. The goal was to stimulate the body to attack abby-normal cells. It worked, the clot dissolved. I assume that's happening now to the alpha synucleon.

Someday I have to tell the neuro about that. She gets a kick out of me telling her about my B1 and melatonin and cinnamon and red light and other experiments.