Simon's post and thiamine HCL.

[parkie13]

scienceofparkinsons.com/202...

Please excuse if it's been already posted. Also talks about Alzheimer's, benfotiamine. Interesting.

[Hidden]

So we should experiment more with Benfotiamine?

[parkie13 in reply to Hidden]

Myself, I wouldn't. I would definitely stick with the water-soluble one.

[freefallmode in reply to parkie13]

Why is that?

[parkie13 in reply to freefallmode]

This is just a guess on my part. Since we are taking a large amount of B1 I would like for it to be excreted and not collected in the fat cells of the body.

[Gcf51 in reply to parkie13]

There's more than one way to look at it. 1) Large dose of thiamine to ensure that excess is flush out, 2) Small dose of Benfotiamine or Allithiamine to ensure some is stored and a medium dose of thiamine so excess is flushed out.

[parkie13 in reply to freefallmode]

B1 - thiamine HCL

[Gcf51]

Conclusion: Our results show that, though benfotiamine strongly increases thiamine levels in blood and liver, it has no significant effect in the brain... Benfotiamine, an S-acyl derivative practically insoluble in organic solvents, should therefore be differentiated from truly lipid-soluble thiamine disulfide derivatives (allithiamine and the synthetic sulbutiamine and fursultiamine) with a different mechanism of absorption and different pharmacological properties. medscape.com/viewarticle/58...

I just received my order of allithiamine and took my first (1) 50mg cap, Maybe placebo effect, but I feel a difference. Probably not going to take anymore benfotiamine. Could also be, I spent 4 hours yesterday and 5 today clearing a 6ft wide area behind my backyard fence (Exercise).