Injections of B1

[Fed1000]

Has anyone had adverse reactions using B1 in the form of injections?

[Lucal]

no adverse reactions for me.

[Fed1000 in reply to Lucal]

Thanks Lucal. How much B1 are you doing? It works? Why did you choose the injections? I forced myself because the pills (900 mg. per day) cause me inflammation. Good things.

[Lucal in reply to Fed1000]

100 ml i.m. al sabato. Non credo fermi il male. Non ho problemi a farmi punture da solo..... Meglio che tante pillole....

[chartist]

Absolutely!

On the "Thiamine / HDT / B-1 FAQ Page", look at question and answer number 28 :

healthunlocked.com/parkinso...

There also are side effects to the oral dosing, but you are asking about the injections.

Art

[rebtar in reply to chartist]

Art -- I'm wondering if you might have thoughts on my situation with B1. I've tried doses from 4K all the way down to 500mg. It was fine for a while (my symptoms are mild so I didn't notice symptom improvement, but hoping for slower/no progression). Then after 8-9 months I started to get stiffness particularly in the hips -- I actually got pain in the hips that woke me up at night. It took me a while to figure out that it was the B1. I've gone off and back on a number of times with the same result. Even waiting more than a month in between intents, when I start again, after a couple of weeks I start to get stiffer joints. Any thoughts? Maybe just not for me?

[chartist in reply to rebtar]

rebtar.

A couple of things that Dr. Costantini said is one, that the correct dose of B-1 would only result in improvement of symptoms and not a worsening of symptoms. Two, he said that even if you worsen, that is an indication that you are a B-1 responder.

If what he says is correct, then you are a responder to B-1, but your dose is now too high and eventually and regularly results in the same worsening of symptoms based on what you said above. The fact that it took 8 to 9 months for the symptoms to appear, based on what Dr. Costantini has said in the past, it would be an indication that the dose was close for those 8 to 9 months.

Dr. Costantini felt that the thiamine actually did repair cells in the body and as such, after months of use and repair by the B-1, it was possible that the demand for B-1 by the body could decline. I'm not a doctor, but if he is correct then it could explain your current situation. Others on this forum have found a similar problem with a worsening of symptoms after months or years of use. When Dr. Costantini was still doing his email consults, he could workout the adjustment of the dose to resolve the increase in symptoms, but that is no longer the case.

If you are not already aware, I think you should know that there are at least three forum members who are using less than 100 mg/day to good effect.

I think it is a huge mistake to assume that you need a specific dose because someone else has stated that you should, other than Dr. C of course! In any case it usually comes down to trial and error, but I think it is safe to say that the majority of forum members who are using B-1, are doing so at a dose that is less than 3 grams/ day.

Given the above, I think that Dr. C would have you lower your dose slightly. Previously he used a few ways to do this, but one way, was to stop completely until the symptom regressed and then start at a reduced dose which in your case could possibly be as little as skipping one dose per week. He might have you pick a specific day that would be easy for you to remember and skip your dose for that day. That is what I saw him do before with another forum member. Another option would be to lower your daily dose by using the 100 mg Thiamine HCI or HCL / B-1 capsules. On the "Thiamine / HDT / B-1 Primer Page" I have a link to a supplier of 100 mg Thiamine HCI/HCL capsules at a fairly good price. Here is a link to that page :

healthunlocked.com/parkinso...

You will have to scroll down that page until you get to the links to B-1 suppliers. Those links are approximately 1/5th to 1/4th of the way down the page.

Art

[rebtar in reply to chartist]

Thanks. I’ll try that.