Parkinsons & Magnesium

[shallotpeel]

Why is magnesium useful to Parkinsons patients?

[Hidden]

shallotpeel,

The following post may answer some of your questions about magnesium and PD.

healthunlocked.com/parkinso...

Art

[sunvox]

The short answer is there is no human clinical research that shows magnesium helps people with PD. People on this forum (myself included) look at research that hints at the POTENTIAL of supplements based on the available research that is usually done in cell cultures and animals. The general theory why magnesium MAY be helpful to PwPD has several parts. First, it is well known that magnesium is key to cellular health that's what this study is saying (and there are many more like that):

ncbi.nlm.nih.gov/pubmed/274...

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Next, it turns out that researchers have found that PwPD often have low magnesium levels in their cells:

ncbi.nlm.nih.gov/pubmed/263...

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so that means perhaps an increase in magnesium will help cells survive, and that is what this study talks about in it's summary of what we know so far:

ncbi.nlm.nih.gov/books/NBK5...

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plus there is other research including real human clinical trials that show magnesium may have other benefits to brain health especially cognition:

ncbi.nlm.nih.gov/pubmed/201...

ncbi.nlm.nih.gov/pubmed/?te...

clinicaltrials.gov/ct2/show...

alzdiscovery.org/cognitive-...

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there is also research showing that magnesium may help block calcium channels, but that was linked in the other reply and that involves another whole theory on PD that I believe is misbegotten.

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I take magnesium l-threonate twice a day. I do not have Parkinson's but another neurological disorder that stems from mis-folded proteins. I had symptoms including poor balance, slurred speech, declining strength, fatigue, and worsening handwriting. All my symptoms are now gone.

[kgold in reply to sunvox]

Sunvox - thanks so much for your commentary and the links!

[2donkeys in reply to sunvox]

Thanks Sunvox for the detailed info, much appreciated. Time to order some more magnesium.

[Hidden]

One very good source for magnesium information is Carolyn Dean, an MD and NMD. She wrote a book called "The Magnesium Miracle." Magnesium is essential for 400-500 biochemical processes in the body and 80% approximately of the population is deficient in it according to her. She formulated her own brand which is a liquid and does not cause diarrhea which most other magnesium formulations and products, be they tablet, capsule, powder do cause. I personally believe she knows more about this essential mineral than anyone else. My husband and I have been taking her magnesium, Re-Max, for several months and are very pleased with it although it doesn't seem to have directly alleviated any of his Parkinson's symptoms. We're just taking it because it is more bioavailable than any other form or brand and because we were deficient in it.

[sunvox in reply to Hidden]

The available human trial was sponsored by the makers so I remain skeptical, but there is extensive research on magnesium l-threonate, and it's ability to reach the brain. Far better than Dr. Dean's formulation in terms of reaching the place a Parkinson's patient needs it the most, the brain.

[12BHOPEFUL]

I take 500mg of Magnesium and it helps calm my Restless Leg symptoms and helps with constipation, both of which are symptoms of my PD.