Biopsies result

[Miti333]

Hi. Can you tell what's the microscopic features for crohn's disease. I mean what results have to be on biopsies to tell it's crohn's. What 's your experience? My results on biopsies were:

1) Terminal ileum : mucosa of terminal ileum with coserved arhitecture,diffuse and nodular lymphoid hyperplasia in lamina propia.

2) Colon and rectum: edema and nodular lymphoid hyperplasia. My GI says this is normal but i checked dr Google and there i found it's something rare in adults. I'm 42 years old. What do you think? It could be sign of crohn's?

[FRreedman]

Do you know your calprotectin results? As we haven't seen the reports from the experts of your colonoscopy or endoscopy, I would be loathe to go against your GI consultant. You can of course ask your GP to arrange a second opinion for you.

[Miti333 in reply to FRreedman]

Thanks. My calprotectin results were 197 in june last year,after 400 in August, 112 in Jan this year and 41 in May. She said it might be because of giardiasis because they found me giardia.

[FRreedman in reply to Miti333]

Well, presumably you are on anti-biotics for that, and you have been told how to self treat. If you are going to ask for advice which contradicts a consultant, you would be wise to tell us all the facts first. If you wait about two weeks or so, and have your calprotectin test done again, you should be able to see the levels going down towards zero. If they are not then carry on with the anti-biotics, and get a blood test done to check whether you still have the infection. If you come back to this forum, with all that information, someone here may be willing and able to offer further information and advice.

[Miti333 in reply to FRreedman]

I've done antibiotics for giardiasis last year on Sept but I just wanted to know if the biopsies results are normal. The biopsies were done this year on April and I repeat giardiasis test and was negative

[FRreedman]

If you are going to use Dr Google, then please use him carefully. The findings you have given do mimic Crohn's Disease, however it is rare to find it in an adults lungs, according to the good Dr Google. I think I would still ask for a further calprotectin test and after viewing the results make a decision to accept the results and decision of the consultant. I sincerely hope you do not have Crohn's because it is one hell of a pain in the butt (Literally). Good luck

[Miti333 in reply to FRreedman]

Thank you very much, FReedman. Do you think calprotectin level could get low without specific meds for ibd?

[FRreedman in reply to Miti333]

Yes, it would depend on what made them elevate, originally. If it was Giardiasis, which originally, caused the Calprotectin levels to rise, then the removal of Giardiasis would, ultimately enable the levels to return to normal or near normal levels.

[Miti333 in reply to FRreedman]

Thank you FReeman. I'm sorry. I'm from Romania and maybe i don't know to put the question in the right way. In case of crohn 's if calprotectin could get between normal limits without specific meds?

[FRreedman in reply to Miti333]

It is very unlikely that the calprotectin levels will reduce, without the cause of them being raised being removed, so if it was raised because of Giardiasis, then the Giardiasis would have to be treated in order for the calprotectin levels to go down. Similarly, if the cause was Crohn's disease, then Crohn's will have to be treated in order for calprotectin levels to reduce. It is most unlikely for the calprotectin level to reduce if you have Crohn's and it is left untreated. Good luck

[Miti333 in reply to FRreedman]

Thank you very much,FReeman. Good luck to you, too.