A slideshow summary of CLL related papers, presented at last year's American Society of Hematology (ASH) Annual Meeting is now available from Clinical Care Options (free registration). It provides a good comparison of how various new drug and new drug combinations work with different classes of CLL patients.
clinicaloptions.com/Oncolog...
Key to Common Abbreviations
CR = Complete Response
DOR = Duration of Response
MRD negative = Minimal Residual Disease negative (i.e can't detect CLL)
ORR = Objective Overall Response (sum of PRs and CRs)
OS = Overall Survial
PD = Progressive Disease
PFS = Progression-Free Survival
PR = Partial Remission
SD = Stable Disease
TTF = Time to Treatment Failure
The purpose of many of these are discussed in the paper: Endpoints for Assessing Drug Activity in Clinical Trials
theoncologist.alphamedpress...
Neil
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