UK Telegraph Newspaper report

[Jm954]

Mike Peters from a Welsh music band The Alarm had CLL for 29 years but was diagnosed with a Richters transformation this year.

He received treatment in the UK STELLAR trial which adds Acalabrutinib to the usual R-CHOP chemotherapy. He's had a spectacular response and his story is here

digitaleditions.telegraph.c...

Information on the UK STELLAR Trial is here:

cancerresearchuk.org/about-...

Jackie

[mrsjsmith]

Thank you Jackie,

Interesting that he was originally diagnosed 29 years ago.

Colette

[Poodle2]

Thanks for sharing, really wish him the best of luck.

[Kwenda]

More at these pages.

The Alarm frontman with his wife Jules who has also recovered from breast cancer.

bbc.co.uk/news/articles/c20...

Also

standard.co.uk/news/health/...

Dick

[TruthJunkie]

Wonderful! Wishing him the best going forward! Thanks for sharing. It reminds us that this disease hits far and wide.

[Eucalyptus22]

As someone who is on Acalabrutinib this is really interesting. Combining it with chemotheraphy and getting to remission is just wonderful. I wonder if remission in this case is uMRD? It will be interesting to see if the NHS will offer this combination as a 1st line treatment or only for those who have Richter's? It is wonderful alone that it dealt with his Richters as this frightens many of us.

May he have many more years to play music

[Jm954 Administrator in reply to Eucalyptus22]

I think offering this combination will be a long way off as the trial is recruiting only very slowly and this is putting the trial in some difficulty moving forward. It means that there may not be enough patients to be able to demonstrate the statistically significant difference and improved survival that would be needed for it to be adopted widely.

Trials in USA are using Venetoclax and that is also showing promising results.

Jackie

[Argulor]

Thanks for highlighting this story. It is heartening to see someone diagnosed at a similar age to me, who has lived so long with it.