Hemoglobin level

[Mvh0406]

Dear all,

I am from Holland. My mum has CLL for 4 years now.

I've read al lot of articles here and I also posted something.

Really nice people on this site who are so helpful!

I have a question .. my mum has a Hemoglobin level of 5.8 at this moment.

Is there someone who can translate this "dutch" level into the american of english level?

If I have the levels I can compare the one of my mum.

Thank you in advance!

Best regards,

Mirjam

[lankisterguy Volunteer]

Hi Mvh0406,

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It is confusing, but this link may help- or see the screen shot from it below

iapac.org/fact-sheet/normal...

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And here is the long detailed explanation of what, where & why

en.wikipedia.org/wiki/Refer...

SNIP:"Units

Mass concentration (g/dL or g/L) is the most common measurement unit in the United States. Is usually given with dL (decilitres) as the denominator in the United States, and usually with L (litres) in, for example, Sweden.

Molar concentration (mol/L) is used to a higher degree in most of the rest of the world, including the United Kingdom and other parts of Europe and Australia and New Zealand.[4]

International units (IU) are based on measured biological activity or effect, or for some substances, a specified equivalent mass.

Enzyme activity (kat) is commonly used for e.g. liver function tests like AST, ALT, LD and γ-GT in Sweden.[5]

Percentages and time-dependent units (mol/s) are used for calculated derived parameters, e.g. for beta cell function in homeostasis model assessment or thyroid's secretory capacity.

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Len

Lab values USA vs EU & SI for Hgb & Hct F= Females M= Males

[Mvh0406 in reply to lankisterguy]

Thank you for the information, I really appreciate it!

[Vlaminck in reply to lankisterguy]

Interesting and thanks. Strange it says we here in US use dl ---??? I've never ever heard any doctor or layperson speak of deciliter. Have you (if in US)?

[AussieNeil Administrator in reply to Vlaminck]

People tend to ignore the units and just mention the value. That can lead to confusion unless the reference range is also included, particularly when it is possible to have both different reference volumes and units of measure (e.g. grams, moles, cells).

The deciliter is most definitely commonly used in the USA - the trigger for commencing treatment (under 10) in your NCCN Guidelines is expressed in g/dl (grams per deciliter).

In Australia and England, we use grams per litre, so that the trigger for starting treatment is haemoglobin dropping below 100 g/l (ten times the reference volume).

Neil

[lankisterguy Volunteer in reply to Vlaminck]

They are on my tests from Weill Cornell NY Presbyterian see the screen shot below

CBC diff results showing g per dL

[johnliston]

Looks to me like it would convert to about 9.346 in U.S. measure

[Mvh0406 in reply to johnliston]

So it is too low, I think.

My mum is not very tired. She does have a cold now. Could that be a reason why the Hemoglobin is that low?

[johnliston in reply to Mvh0406]

I really couldn't say, but it's low enough where she should ask a doctor.

john

[Mvh0406 in reply to johnliston]

Next week she will see the doctor.

[Mvh0406]

Thank you for your comment!

5.8 is millimol per liter, is that what you mean?

[Vlaminck in reply to Mvh0406]

Could millimol be same thing as ml (milliliter or 1/1000th of a liter) or mg (milligram or 1/1000 of a gram)?

[Skyshark in reply to Vlaminck]

Mole is the unit for counting atoms, molecules and apparently in Holland cells. Atomic mass and number of molecules are linked by Avogadro's number, 6. 022 × 10^23.

A mole of Veneloclax is 868.44 grams, while BTKi drugs are around 440 - 480 grams, so about half the size. I have no idea what the atomic mass of a Hg cell is (wiki does).

bbc.co.uk/bitesize/guides/z...

so from the wiki

en.wikipedia.org/wiki/Hemog...

"Results are reported in g/L, g/dL or mol/L. 1 g/dL equals about 0.6206 mmol/L, although the latter units are not used as often due to uncertainty regarding the polymeric state of the molecule.[92] This conversion factor, using the single globin unit molecular weight of 16,000 Da, is more common for hemoglobin concentration in blood. For MCHC (mean corpuscular hemoglobin concentration) the conversion factor 0.155, which uses the tetramer weight of 64,500 Da, is more common."

Men: 13.8 to 18.0 g/dL (138 to 180 g/L, or 8.56 to 11.17 mmol/L)

Women: 12.1 to 15.1 g/dL (121 to 151 g/L, or 7.51 to 9.37 mmol/L)

Children: 11 to 16 g/dL (110 to 160 g/L, or 6.83 to 9.93 mmol/L)

Pregnant women: 11 to 14 g/dL (110 to 140 g/L, or 6.83 to 8.69 mmol/L) (9.5 to 15 usual value during pregnancy)

A "dL" is a decilitre, 1/10th of Litre.

[Mvh0406]

Yes I know about the different measurements in laboratories.

My mum is not very tired. That is what surprises me. Next week she will see the doctor.

Thank you! I am very blessed with my mum. So I really like to help her.

[thb4747]

Hi, I’m in NZ so our system of measurement should be the same. Here, when HGB goes below 8.0 they begin treatment with blood transfusions. I’ve gone below that number 3x over the past 17 years or so and had blood transfusions each time to get back up over 8 — 18 transfusions in total. I’m sure her doctor will want to address this. Good luck.

[Mvh0406 in reply to thb4747]

Thank you for your answer! I think the doctor will start treatment now afther 4 years wait & see. Are you doing well now?

[thb4747]

Yes I am thanks. Best wishes to your mum.