Anyone has followed Rituxan -Venetoclax treatment with good results?

[unairdefamille]

I am terrified to start new treatment because of afib due to Calquence (Alcalabrutinib). Thank you for any reassurance and bless you all. 🙏🏼💚

[lindalou5]

Have you been treated for the AFib with any success? I am still on Calquence from two years ago after in hospital with AFib. I have minor episodes of the afib, take flecainide and have been fortunate that I am managing. I also would like to know the next meds for CLL if AFib gets really bad. Good luck with help on this.

[unairdefamille in reply to lindalou5]

well, I got a beta blocker and blood thinners and a half dose of Calquence. So fat so good 🙏🏼🤞. Best of luck to you 🍀

[lankisterguy Volunteer]

Hi unairdefamille,

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You can read many of the past postings on this subject here:

healthunlocked.com/cllsuppo...

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It's probably our most tested, fixed duration, combination treatment in use today. Many patients with heart or blood pressure issues have been treated successfully and have remissions of 2 to 5 or more years before needing another round of the same treatment.

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And this posting covers the clinical trial data comparing the different combinations:

healthunlocked.com/cllsuppo...

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Len

[unairdefamille in reply to lankisterguy]

Thanks Len, you are a trove of knowledge. I will will read up on it. Bless you 🙏🏼💚

[roszika]

Best thing I ever did was to go on v for 2 years and rituximab for 6 months went into remission in Nov 2019 and still am

[Tchapman in reply to roszika]

Did you ever have afib or blood pressure issues?

[unairdefamille in reply to Tchapman]

Yes I did with Alcalabrutinib.

[roszika in reply to Tchapman]

No

[Bluegillking]

I did undergo rituxan treatments last year for severe anemia caused by CLL. I must say I had very good results with the treatments. My hemoglobin counts went up and have remained pretty close to normal since then. The only side effect I had was during the first treatment (this is very common) called "shake and bake". It is a case of nausea followed by a severe case of the chills. This is taken care of immediately by a care team that is right there. After that you will probably sleep for the rest of the treatment. The rest of my treatments went without any problems whatsoever and I even drove home on my own. I would recommend the rituxan and would take it again if needed. I hope this was helpful and wish you the very best of luck with your treatments. 🙂

[unairdefamille]

Thank you and bless you, these are wonderful news. Not looking forward to shake and bake, but at least I am warned. 😊

[wassupdoc]

Hello - Others have replied with their Calquence experience but I was treated with V + Obinutuzumab (Gazyva) in 2016 and part of 2017, and still in remission. Obinutuzumab is similar to Rituxan.

[unairdefamille]

Thank you, I hope you stay in remission for a long long time. 🙏🏼🌟💚

[gardenman68]

I have had great luck with rituxan and venetoclax. The very first rituxan treatment left me very tired and I slept most of the day. After that I was good. The venetoclax has put me in remission for over a year now. I only take half the required dose because of a skin rash, but it doesn't seem to make a difference. I take it at night so it doesn't ruin my day with possible upset stomach.

[unairdefamille]

Thank you dear gardenman 68, very encouraging. ALL THE BEST TO YOUas you continue to thrive 💚🍀