Richter's Syndrome! One pill, Triple Combination Therapy is in clinical trial for Richter’s Transformation & De Novo Large B-Cell Lymphoma

[bkoffman]

Richter's Syndrome! One pill, Triple Combination Therapy is in clinical trial for Richter’s Transformation and De Novo Large B-Cell Lymphoma with impressive results. In this ASH 2020 In this video Dr. Mato tells us that his clinical trial introduces the concept of “synthetic lethality,” where multiple targeted agents are used at low dosages to block different pathways and achieve the ability to kill cancer cells without the associated toxicities of putting three drugs together at the usual dosages. cllsociety.org/2021/01/ash-...

[Jm954 Administrator]

Great news and, at last, something innovative and hopeful

[bennevisplace]

Very interesting, thanks.

Do you think that the "synthetic lethality" approach could be the way forward for treating blood cancers generally? An effective drug combination with mild side effects, taken as a single tablet, has to be the CLL patient's dream.

[bkoffman CLL CURE Hero in reply to bennevisplace]

I am hopeful.

[Fran57]

Very promising news. Thank you.Stay safe,

Fran 😉

[kimiD]

Thank you for sharing!