Moderna Vaccine latest: This FDA briefing... - CLL Support

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Moderna Vaccine latest

bennevisplace profile image
10 Replies

This FDA briefing document, for consideration of an Emergency Use Authorisation (EUA), appeared on the web in the past few minutes fda.gov/media/144434/download

and this article deals with the Moderna vaccine's durability of response in phase 1 trials nejm.org/doi/full/10.1056/N...

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bennevisplace
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10 Replies
Justasheet1 profile image
Justasheet1

Good info here. I’m hoping to see the Moderna vaccine soon.

bennevisplace profile image
bennevisplace in reply toJustasheet1

It will be free in the US I believe. And 200 million doses secured. UK has 7 million.

Justasheet1 profile image
Justasheet1 in reply tobennevisplace

Do you know if that’s a 2 dose regimen?

bennevisplace profile image
bennevisplace in reply toJustasheet1

Yes it is theverge.com/2020/11/20/215...

Big_Dee profile image
Big_Dee

Hello bennevisplace

That is good, as the Moderna vaccine is supposed to have less demanding storage requirements than the Pfizer vaccine and slightly better precent response. Very Merry Christmas.

bennevisplace profile image
bennevisplace in reply toBig_Dee

Thank you Big_Dee, the same to you, and best wishes for 2021.

Justasheet1 profile image
Justasheet1 in reply tobennevisplace

Any more info on the Moderna vaccine? I’m poised to get it in the next week or two.

Dr. Weirda at MDA, my doc, is recommending it for All his patients.

Jeff

bennevisplace profile image
bennevisplace in reply toJustasheet1

Good that you are getting the vaccine so soon. Forbes is running a story forbes.com/sites/williamhas... about the rate of decline in antibody levels after vaccination, but this data was known to the FDA well before they approved the Moderna vaccine. Unsurprisingly the most rapid decline is in older age groups.

The good news is that the US government ordered 200 million shots, there is Pfizer BioNtech, and there are other vaccines coming. They should be able to get 80 pct of people vaccinated in 6 months, then they can give booster shots to those who need them.

Justasheet1 profile image
Justasheet1 in reply tobennevisplace

I thought that circulating antibodies always drop off and the memory T cells kick start the antibodies again if you are exposed again.

bennevisplace profile image
bennevisplace in reply toJustasheet1

This is pushing past the limits of my very limited knowledge. But I think both antibodies and virus specific T cells tail off at different rates for different viruses.

Someone better informed please come in on this.

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