Professor Anna Schuh, consultant haematologist, Chair of the NCRi CLL clinical research group and Director of Molecular Diagnostics at Oxford University.
Dr David Allsup, Senior Lecturer in Haematology and CLL lead at Queens Centre for Oncology and Haematology at Castle Hill Hospital, Hull.
Helen Knight, CLL Nurse Specialist at Nottingham University Hospital.
The panel will discuss and answer your questions about how CLL is treated and how care is provided today; what is expected moving forward as lock-down is lifted; clinical trials; trials restart and new treatments becoming available.
Make a note in your diary now!
Jackie
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Jm954
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I just completed my 6 cycles of RCVP chemotherapy for CLL. Each time i went to hospital for administration of chemo there was increase in size of my spleen and abdominal lymph nodes after they had subsided just after 2 or 3 days chemo administration. my doctors are considering another treatment option for. what is your suggestion on my treatment option?
Also what is the current recommendation of scientists for CLL patients to receive CRISPR/cas9 gene editing treatment. Looking forward to hearing from you.
R-CVP (rituximab, cyclophosphamide, vincristine and prednisone) is not a usual treatment for CLL. Was this given because you had an atypical CLL presentation? (This could influence your next treatment choice).
CRISPR/cas9 gene editing treatment is experimental and you would need to know the specific DNA error needing correcting and a way to only target that mutation location in just CLL cells. With the huge range of possible DNA errors involved in causing healthy B-lymphocytes to become cancerous CLL cells, I wouldn't think CLL would be a high priority target for such research.
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