I will be going for a follow-up visit with my specialist at UPENN after new blood work to check for mutations and to discuss treatment options. My questions is: Based upon my SLL parameters what drugs other than ibrutinib may be an option?
I am a female 63, diagnosed in 2008 with SLL. I was treated twice with Benda and Rituxan 2011-2012 and 2014 -2015 - I am UNMUTATED. cd38+ 34%, cd20+ dim. NO OTHER HIGH RISK MARKERS. RItuxan did not work for me. My SLL came back during the 2 1/2 yr maintenance phase. Lymph nodes are getting larger on Pet Scan but not brighter. I am now on IVIG for frequent infections and I am starting to deal with fatigue again. I have lost 20 pounds since January. NO night sweats. I KNOW that more treatment is in my future, I just don't know which drug is best. My issues w Ibrutinib are cost especially when I go on Medicare in 2 years and more important, the fact that it can just stop working, or worse yet cause the disease to transform to something worse.