I'm waiting to find out if I'm IGHV mutated or not. If I am I'm less willing to undertake FCR. Does anybody know anything about the btk inhibitor ACP 196. How is it different to Ibrutinib?
ACP 196: I'm waiting to find out if I'm IGHV... - CLL Support
ACP 196
Written by
Kenn123
To view profiles and participate in discussions please or .
Read more about...
1 Reply
•
I am non mutated and started taking ACP-196 in February 2015 as part of a phase 1 drug trial. It is a more targeted second generation BTK. This means that there are fewer side effects. I have not had any adverse side effects. In fact, I have had several positive side effects - sinuses cleared up and my eczema is less severe. I have attached a link to an interview of Dr. Byrd who published the first ACP-196 phase 1 test results. This is from December 2015. To my knowledge nothing has changed in the last 10 months.
Not what you're looking for?
You may also like...
ACP 196 treatment
Hi Every one I am looking for people who are taking ACP 196
This is a trile medication for CLL my...
ACP-196 (BTK inhibitor acalabrutinib) Trial
Well, my husband is now at the 12 month point on this trial. Bloods etc are all OK. He had a bone...
ACP-196 (Acalabrutinib) TRIAL - 31st monthly cycle achieved with full remission
Not been here for a while as nothing really to report. Husband is still on the ACP-196 trial and...
Have Johnson & Johnson and AstraZeneca done one better than AbbVie, purchasing 55 percent of Acerta Pharma for acalabrutinib (ACP-196)?
"Earlier this year, AbbVie won an intense bidding war for Pharmacyclics, paying $21 billion for...
PI3K inhibitors (idelalisib,copanlisib, duvelisib, parsaclisib, umbralisib, zandelisib, ACP-319) in CLL: where do we go from here?
While we have never been as spoiled for treatment choice as we are now, PI3K inhibitor safety is...
Arm pain, leg pain, wrist pain, achy ribs, night sweats....( Last bloods were in July and they were super), what's going on? 
Having a six to seven hour infusion of Rituxan and something else tomorrow.
What to expect.
Night sweats
Husband on O+V, month 5, WBC Morphology abnormal
