Low fat, high carbs; high fat, low carbs, paleo, Mediterranean...the dietary guidelines are numerous and confusing. Some people swear by one or another and the medical community is stuck on low fat diets. The truth is different for each of us because of our genetic make up.
Diet recommendations from the medical community and the media are generalizations. If you want to know the best diet for yourself, you must get a gene test for the Apo E Genotype.
Here's a link to a research piece - you don't have to read the whole thing, just go to pages 4 and 5 which contain a chart that shows the optimal diet for each genotype:
lipidcenter.com/pdf/Apo_Ev2...
Once people realize that determining their Apo E genotype is critical to diet implementation we can stop getting these broad generalizations on how and what you should eat.
What is interesting in the chart is that for those with the Apo E3/E3 genotype, lifestyle modification is sufficient for cholesterol control and statins are NOT required. However, for some other genotypes, statins ARE required, and yet for others, only CERTAIN statins work.
Do a Google search and find out where you can get a test to determine your Genotype so you no longer have to speculate whether or not you need to be on statins and what your optimal diet should be.
If the human body produces 80 % of cholesterol on demand and 20 % from food intake, my how question is "What is the reduction in cholesterol from food intake?"
The second questions " How can the food intake control the body on the 80% of cholesterol production on demand?"
There has been many article on regular exercise, food in take and drinks intake control for healthy life. Some make good reading!
Final question, "why is human body demanding for more cholesterol?"
The answer to your questions is in the link I provided. It is a matter of gene sensitivity. The recommendations in the link were not solely on food consumption - they also related to need for exercise, sensitivity to alcohol, and statin use - depending on Apo E Genotype.
Reading the whole document might help you better understand. You may also try this website:
gbhealthwatch.com/GND-High-...
You may also wish to read the book featured in this website:
integrativemedicineinc.com/...
If I read the first link correctly - being of 100% caucasian extraction, it seems that 80% of caucasians fall under the E3/E3 and E3/E4 genotypes? - which the webpage then goes on to suggest a "balanced" diet of equal quantities of fat and protein and double quantities of carbohydrates - which is basically as I have understood for decades. Once again - I must say that I don't like the use of the term carbohydrates as used in most of these articles because of the vast generalisation. There is a big difference between a can of soda loaded with sugar and a bowl of oat porridge
You'll only know with certainty if you do the gene test. Apo E4 also raises the spectre of Alzheimer's risk...interesting stuff.
At first glance, it looks like E2 and E4 both seem to be associated with increased TG. I have low and surprisingly stable TG, so am I right to suspect I'm E3/E3? Disgustingly common, yet again!
I agree Bazza, I restrict Carb's but the simple variety only not complex carb's like porridge
What is the reduction in cholesterol from food intake? Pretty much nothing in my experience. The NHS used to advise limiting cholesterol intake (restrict consumption of egg yolks and so on) but it seems that most people's bodies adjust cholesterol production to compensate, so it's no longer part of the guidance.
How can the food intake control the body on the 80% of cholesterol production on demand? Well, we know food intake can influence cholesterol production and conversion in various ways: from functional foods like stanols and sterols that dupe the body into thinking it's getting cholesterol from food, through old-fashioned bile acid sequestrants that make the body step up cholesterol conversion to replace the acids, to statins which are still essentially a refined form of a food that inhibits production. Then there's all the claims about various diets affecting various people in various ways, which are probably mostly true for them but it's hard to know who should eat what diet.
Why is human body demanding for more cholesterol? It might not be. In people with damaged cholesterol receptors on the liver, it's that the body is underestimating how hard it needs to work to remove enough.
Let us hope some one will write an answer to your questions!