Is ALT normally tested with LFT/Liver ... - British Liver Trust

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Is ALT normally tested with LFT/Liver blood tests?

Shoe2 profile image
10 Replies

I had LFTs/ liver blood tests done but no ALT included. Is this normal or should it be ordered additionally? Thanks

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Shoe2
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10 Replies
AyrshireK profile image
AyrshireK

Are you sure ALT is missing? It is usually one of the standard liver tests - it is normally listed as Alanine Aminotransferase (ALT) giving it it's fully title. ALT is more liver specific than AST which sometimes is missed off and not always tested. AST is :- Aspartate aminotransferase.

Katie

Shoe2 profile image
Shoe2 in reply toAyrshireK

Thanks Katie. Mine has Serum globulin, Serum total protein, Serum Albumin, Serum total bilirubin, Total Alkaline Phosphatase (ALP), AST serum level and Serum gamma GT.

I was looking back over tests a dietician I was referred to by gastroenterologist thinks my GI symptoms could be Bile Acid Malabsorption.

Thanks

AyrshireK profile image
AyrshireK in reply toShoe2

Unusual they've not done ALT as it is one of the main liver ones.

Shoe2 profile image
Shoe2 in reply toAyrshireK

Thanks. I will ask GP to run that test also. Just to be sure in case it indicates liver function problems that may explain low bile and my digestive issues as CT scan said no dilated or blocked bile ducts.

MINTVCX profile image
MINTVCX

Both ALT and AST are considered to be standard LFT. Both can be used to calculated FIB-4 which is better to check liver than alone ALT. Of course is not enough but a good star point (especially in NALFD).

I think is an old attitude to test only ALT and if normal to say it is ok.

Geodesic2024 profile image
Geodesic2024 in reply toMINTVCX

In the UK now in my experience GPs (and hospital consultants) will generally order ALT (alanine aminotransferase) and ALP (alkaline phosphatase) but not AST (aspartate aminotransferase), as well as bilirubin, GGT (gamma-glutamyl transferase) and albumin, globulin and the sum of these = total protein. AST may be added as well but less common these days it seems.

daveyboixx profile image
daveyboixx

I haven't had ALT included on any of my most previous LFT's also.

Geodesic2024 profile image
Geodesic2024 in reply todaveyboixx

That's very unusual - ALT is the one most associated with fatty liver.

Shoe2 profile image
Shoe2

I asked my GP today. He said AST is normal in LFT and ALT only run if AST shows to be high !

Geodesic2024 profile image
Geodesic2024 in reply toShoe2

Other way around I think you'll find, certainly in UK!

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