can allergies affect liver and cause problems to it?

[Avdx]

Hello,

sorry if it's a dumb question, I'm still pretty new with liver diseases.

So I read that allergies can affect the liver and causing problems to it, but of course I don't want to just ask Dr. Google about it. I wrote about my spider nevi on another post what I got around age of 14 on the chest, upper back, shoulders and upper arms areas.

I have 4 known allergies and probably I have them for a very long time. These includes Ragweed, cat hair, soy and oil seed allergy also more than likely wheat intolerance. I also have the post nasal drip, and the average symptoms when I get in contact with these things (ragweed is far the worst for me then cat hair) nowadays its better but for years it was very bad.

I had gastroscopy around 2 years ago and it showed h. pylori negative mild (erosive) gastritis and one part of my villi damaged, maybe caused by one (probably soy) of my allergy.

I don't really know why I Googled that but this seems more logical for me than Hereditary Hemorrhagic Telangiectasia, what doctors are trying to check. My question would me, can allergies affect the liver?

Thanks!

[Fibro2021]

Hello,

If you have a wheat intolerance, then it is probably due to an intolerance to the gluten found in wheat or celiac disease. Have you already been tested for celiac disease or gluten intolerance? In celiac disease, secondary liver damage can occur and this leads to non-cirrhotic portal hypertension as described in many medical articles.

[Avdx in reply to Fibro2021]

Hey,

The only one test I had for Celiac is blood test which was negative. I have symptoms for wheat/gluten like diarrhea, sometimes strong headache, also sometimes constipation. After the test I went gluten free completely and I still am, sometimes I eat wheat/gluten to test the symptoms but thats all. I dont think I have Celiac tho, as well as my doc didnt think I have it (maybe NCGS).

What I am thinking is, if these allergies affected my stomach (which is confirmed due to gastroscopy-and I didnt even know anything about gastritis) why couldnt they affect intestines or even the liver? I think because these allergies were untreated ( I didnt know about them until test), they could cause problems in some organs. Because of allergies I have very elevated eosinophil levels too.

[Fibro2021 in reply to Avdx]

It's possible that NCGS may affect the liver in the same way as celiac disease. Gluten intolerance can also contribute to allergies to other substances through intestinal permeability. I would like to add that the only diagnostic method for NCGS is a gluten-free diet, since laboratory tests are not informative.

[Avdx in reply to Fibro2021]

Yes, thats why Im trying to find logical explanation about the apperance of spider nevi with that is already confirmed and because of what you said (right), NCGS can not be confirmed with blood test.

What I know is: as infant I had cows milk allergy what I outgrow and it was replaced with soy. At age 5 ish they first mentioned slightly elevated soy IgE (so basically I was allergic to it) but for some reason it has been ignored. I think the other allergies are cross allergies as well as if I have NCGS, that one too. So basically they are with me for a very long time and thats why I think there COULD be a connection (between them and spider nevi and the very hard weight gain thing)

[Fibro2021 in reply to Avdx]

In this aspect spider nevi may be symptoms of portal hypertension and should be considered as a working hypothesis.

[Hdon]

Have you had your iron levels checked? Iron overload (Haemochromatosis) can cause liver damage and consequent Spider Nevi, which were one of my symptoms at diagnosis.

[Avdx in reply to Hdon]

Hey!

Both b12 and iron (and ferritin) were normal, but some months ago I had low level folate, I even had to take vitamins for it.

[Avdx]

Wanted to give a small update:

I went to a gastroenterologist today, he absolutely agreed with me that spider nevi can be a sign of liver problem, and will be checked also more than likely I will have colonoscopy aswell. When I told him about Hereditary Hemorrhagic Telangiectasia, he just checked my tongue and because there weren't telangiectasias, he just said "it's not that" And I'm totally agree. What he found abnormal that usually the telangiectasias aren't appearing at that age when I got them.

I'm pretty sure one of the most serious reasons behind everything are my untreated allergies.