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Does anyone split their dose of Losartan ?

Myrtle13 profile image
6 Replies

Hi All

Looking for advice please

I take 10 Lercandipine, in the morning , 20 Propranolol twice a day & 25 Losartan at bedtime without any side effects. As my BP has now risen my GP wants me to either Increase dosages or find a 4th medication. I’ve tried increasing the Losartan to 50 or even 37.5with better readings but quite debilitating side effects ,headaches and joint & muscle pain in my legs,neck & lower back. I ve triec splitting the dose today taking 25 Losartan last night & 12:5 with the Lercandipine this morning but my Blood Pressure has been high all day.160/82 I would take 25 twice a day if there were no side effects. I ve tried 3 additional meds but all had side effects so increasing my existing meds seems to my only option. I asked the pharmacist about and she thought it was maybe because 12.5 is too low or maybe to do with takin g Losartan with Lercandipine ?

Does anyone have split their Losartan dose please?

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Myrtle13
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6 Replies
Happyrosie profile image
Happyrosie

you are asking what individuals do and you are also asking a small audience, so any responses might be skewed. You are very wise to talk to a pharmacist as they know more about medicines and their side effect and inter-reactions than doctors.

You might get some insight from Blood Pressure UK, the specialist charity. Also, the pharm attached to your doctor’s surgery might be helpful (if this wasn’t the one to whom you’ve already spoken).

Myrtle13 profile image
Myrtle13 in reply toHappyrosie

Thanks for replying much appreciated. I take your point I just wanted to know if anyone does split their Losartan and whether they had side effects.or if their BP readings were affected. I know we all respond differently when it comes to side effects . Thanks again

Nick234 profile image
Nick234

I guess we all react differently

I started with Losartan at but after 3 months my GP upped it to 50.

ZERO side effects after a further 6 months and it has done the trick bringing BP down from 155/82 to around 132/77

Myrtle13 profile image
Myrtle13 in reply toNick234

Hi , glad to hear it’s working for you maybe I need to give it more time for the side effects to lessen .thanks for replying

michellefisherm profile image
michellefisherm

Wishing you good health. I used to take Metoprolol 50mg extended release and Losartan 25mg at night but the BP was dropping too low. So Losartan was reduced to 12.5mg at night and it has been working for me.

Myrtle13 profile image
Myrtle13 in reply tomichellefisherm

Glad it’s working for you maybe I just need to give it time for the increased amount to work Also I had a blood test yesterday and my GP texted me today saying my sodium level is low so I need to add some salt to my food ! & and replace water with fruit juice for a week then have another blood test. Looking at the symptoms of low sodium this might explain some of the “side effects” I,m experiencing such as tiredness,headaches and lack of appetite. So I’m tucking into the olives tonight! Thanks both for replying

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