. I was first diagnosed in 2000.My meds are currently Symbicort 400/12 and Spiriva. Prednisone and Zithromycin when having an exacerbation. I have tried Onbrez, but it made it harder for me to breathe for at least an hour and I did not see any benefit. Also I have taken the usual Ventolin and Atrovent both a spay and nebulizer but without any noticable improvement. I woukld be really interested in what meds others are taking.