Lansoprazole links to dementia

[Freshorangejuice]

Interested to know whether any GPs have advised patients not to take Lansoprazole given that various studies suggest their is a higher risk of dementia for patients who are on long term use of proton pump inhibitors eg Lansoprazole and others?

[Happyrosie]

that’s interesting. Can you point me to the relevant study? Or NICE article? As I’ve been on PPI for a long time.

[Freshorangejuice in reply to Happyrosie]

There are quite a few studies but here is just one:

healthline.com/health-news/...

[Happyrosie in reply to Freshorangejuice]

Thanks for this! On the basis of that study I personally doubt whether GPs would advise their patients to avoid PPI’s as the alternative might be worse ….. but next time I have my annual review with the pharmacist at my GPs group of surgeries I will mention this.

[Lowerfield_no_more]

Very similar post here from 2 days ago.

healthunlocked.com/bhf/post...

My position is I have been taking PPIs for over 15 years for reflux disease. It keeps my symptoms at bay and has apparently stopped further development of Barretts Oesophagus which I contracted before I started on PPIs. I don't suffer any apparent side effects and am certainly not showing signs of dementia. Taking medication comes with a risk caused by side effects, and that has to be balanced against not taking it. In my case if I stopped PPIs my life would be a misery and I would be in danger of an advancement from Barretts to full Oesophageal cancer, or another form of this disease. I am aware of other medication that can perform the same task as the Lansoprazole I currently take, but that other medication will no doubt come with it's own set of side effects. So I will stick with PPIs. And I have not had a medication review which has suggested I consider Dementia or any other long term side effects, such as Osteoporosis which another member mentioned in the linked thread above. But my medication reviews as far as I can see are more a tick box exercise for my GP surgery assuming they take place at all, all conducted in a very passive manner.

[Chorkie22]

I have been taking Lansoprazole with great success for approx 3 years, however, last week my pharmacy refused to give it to me & told me l had to go to the GP. He told me that l can no longer take it as it is believed to cause cancer in some people. He has prescribed me Levogastrol 25mg to be taken twice a day. I was horrified to learn (via Google) that this is prescribed for various mental health conditions (including Schizophrenia). Having battled with chronic depression in the past & now depression free & not on any medication for this, l am terrified that this new medication could alter my brain chemistry? I am so upset because Lansoprazole worked like a miracle for me. I can't get an appointment to discuss this again for 3 weeks.... today is the first day without Lansoprazole & taking Levogastrol instead & by mid afternoon l was already experiencing mild reflux! Fed up & confused!!! 😪