I have neuro Bechets. Diagnosed September 2014 (but had symptoms for 20 years before that). I was taking cellcept and warfarin for the past 2 years, but finally -after further clot in the lung and an internal bleed -it was acknowledged that these meds weren't working and I was finally referred by the hospital who were treating me (who basically didn't know what to do) to a vascular specialist who is treating me with methotrexate and infliximab and has thankfully taken me off the other meds. I am also on Prednisolone at the moment -started at 100mg in March tapering down. Has anyone else taken these meds and how did it go for them? I had bad chest pain which has gone away now but I'm very very tired. My legs feel like lead and I get tightness in my right shoulder/neck if I try to do much. I'm really struggling with it and I'm not working either so I can't blame it on that. Ive been told that the infliximab takes 6 months to work and I've been having the infusions since March. I'm finding this very difficult -I cannot return to work at the moment and my quality of life is poor as I make plans to go out etc and then I just can't. I am praying that I will improve and find this such a lonely disease as I've never met anyone who has it. I'm sorry for moaning on but any advice would be really welcome. Thanks.