About dalfamridine for SCA

[xiaoduoyu]

Has anyone ever eaten dalfampridine? How does it work

[wobblybee]

This is also known as Ampyra....4-AP...Fampridine

Generally prescribed for MS in the UK (my Neurologist confirmed this) But..I have seen a post from someone in the UK, whose Neurologist applied for special funding for ataxia.

Dalfampridine is used to improve walking in people who have multiple sclerosis (MS; a disease in which the nerves do not function properly and may cause weakness, numbness, loss of muscle coordination, and problems with vision, speech, and bladder control). Dalfampridine may be used alone or with other medications that control the symptoms of MS. Dalfampridine is in a class of medications called potassium channel blockers. It works by strengthening the signals sent by the brain through nerves that have been damaged by MS.

medlineplus.gov/druginfo/me...

[PatsyIpswich]

I struggle to understand how it can help when the cerebellum is the cause

[wobblybee in reply to PatsyIpswich]

The person I referred to was prescribed Fampridine..

He has Acquired Ataxia due to a ‘brain infection’...and has symptoms consistent with Cerebellar Ataxia.

Copied from a Support Group..

Beryl Park yes the neurologist applied direct to the CCG about a trial of 3 month funding they then tested improvement and because it showed to be working they agreed to continue prescribing I get a 4 month prescription at a time and it costs the nhs around 400 a month for the tablets

Licensing and availability

Fampridine is a drug that has been shown to improve walking speed for some adults with multiple sclerosis.

It has been approved for use by NHS Wales and NHS Scotland for the improvement of walking in adults with MS who have an EDSS between 4 and 7. It is not currently available on the NHS in England or Northern Ireland.

In 2018, the patent on fampridine expired, and a cheaper version of the drug, called dalfampridine, was developed and licensed in the US.

mstrust.org.uk/a-z/fampridi...