I have SCA7/r43 and been testing Lions Mane about a decade now.'
For me it affects like this: after 3-4 days after the dose the balance gets very significally better, but unfortunately only for 2 days. I have been avoiding the constant usage. (scared about the increasing tolerance) Last years I take a capsule per week.
I have bought a couple of times a similar product in Mexico. It works even better, but last year I couldn't make my visit. Hopefully next year. Happened 2014 in Sonora Market in Mexico City that I managed to buy a bag of natural fungus like mushroom (very suspicious looking) which worked very well. Unfortunately I never found it again.
If anyone have any experiences about growing tolerance issue, please advice.
Also CBD for SCA7 would be very interesting. So far I had almost 0 benefit from CBD oil or other extracts.