Upcoming USA study for LDN and arthritis pain

[ITYFIALMCTT]

I was interested to see that there's a clinical trial protocol (not yet recruiting) in the USA to assess LDN (low dose naltrexone) for the relief of arthritis pain (osteoarthritis; rheumatoid, and psoriatic).

It's a small trial but they've made it randomised and crossover so that's a decent trial design. I'll be interested to see what happens during the recruitment phase and any outcome. I'll say upfront that I don't know enough about LDN to understand whether 4.5mg is an acceptable dosage and if it's feasible to expect people to experience relief during the 8 weeks they're scheduled to be on it (they'll be on placebo for the other 8 weeks).

clinicaltrials.gov/ct2/show...

[Sewnsew]

Hi ITYFIALMCTT , I have taken LDN for quite a while now, it is reported to help with autoimmune thyroid disease, Fibromyalgia among other things. I started on a low dose 0.5mg and increased slowly up to 4.5 mg. This seems to be the maintenance dose recommended. I have now stopped it as I don't really think it was helping me and I was only able to get it privately, so cost was also an issue.

I also have arthritis and I can't say I noticed any change in the pain while taking LDN. Obviously this is just my experience and I believe it does help some people.

For more information see link below.

ldnresearchtrust.org