Hi. I am new to this community but wonder if anyone can give me advice on the best way to treat pain in my wrist caused by arthritis. I had a giant cell tumor removed from my wrist twice (12 and 10 years ago) and due to the location and size of that, and resulting bone graft, I have marked arthritis in the wrist. I am 43. Generally my pain is manageable day to day, but I get flare ups and pain. I have a splint which I wear when it is bad, but can't get any relief from standard medication.