RA for 4years with nonstop pain

Hi, I'm 51years female. Been on all kinds of medicines that treat RA. Unfortunately nothing helped to control inflammation nor pain. Tried biologics too. Cimzia and mabthera did nothing at all. Now I'm having actemra infusion every month. Nothing changed after 2 infusions. Any one felt better using actemra? How long do I have to wait to feel better?

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