AF Association
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Anticoagulants and COQ10

Hi Everybody

I've read on here and elsewhere about the benefits of COQ10 for people with AF. However I went into Holland and Barrett yesterday to buy some and when I asked them to check contra indications etc they said I shouldn't take it if I'm on an Anticoagulant which I am (Rivaroxaban). Has anybody else got any experience of this? Also has anybody found COQ10 beneficial? I'm also on Bisoprolol.

Thanks in advance


13 Replies

Yes - I was recommended to take it by my EP who also prescribed anti-coagulants. I had everything checked by my pharmacist for contraindications.

Personally I wouldn’t buy anything from H&B - if you are going to use supplements know how they are manufactured and what fillers are used and how their ingredients are sourced.

Names of reputable manufacturers- Nature’s Aid, Boots, Lambert’s, Solgar. There are others but they are all of good quality.

You can also buy the active ingredient Ubiquinol as a supplement but it is more expensive and I found no noticeable difference to COQ10 but everyone reacts differently.

Check all supplements with your normal pharmacist for contraindications.


Thank you very much CDreamer. I'll look into that. It's good for heart health generally isn't it and helps prevent cancer?


It is an enzyme which the body produces naturally but as we age, like everything else, the body doesn’t produce as much.

1 like

Thanks for that.

The article does say that it (COQ10) can reduce the affect of anticoagulants but I guess that it is all relative to the benefit that COQ10 provides for each person.

Thanks for your help again


Not always seemingly CD. Surely you've read this?


No but Doc Google has a pile of stuff on this and I'm not surprised he said that

Not seen chapter and verse

HB very pricy


Google is bad for your health . Surely everybody know this? I have been taking CoQ110 for longer than I have been taking warfarin (15 years) and my INR has been stable.


Been taking it for some 8 years. Am on Warfarin and Bisoprolol - no problems.


There was a Japanese study that found people who had a heart attack had very low levels of CoQ10. It was suggested that CoQ10 was necessary for heart health; that of course could be association. I started taking it many years ago when I read that CoQ10 had a positive effect on mitochondria. At that time I was doing quite a bit of cardio exercise and taking 200mg per day. Since the stroke I now take a NOAC (Pradaxa), do less cardio work but as I'm 71, I take 100mg daily. Neither EPs or the Neurologist have said that I shouldn't take CoQ10.


Thanks for that, very helpful


I am so pleased that health shops like H&B are taking notice of the risks some of the products pose to customers on anticoagulants. I had an experience many years ago when I visited a smaller health food store and they cheerfully handed over a product contraindicated for those on anticoagulants. I pointed out politely that health food /remedies can be potent and indeed very harmful to some people. They took this on board and it is good to know that customers are being advised about taking ginseng, St John's Wort, COQ10 etc.Anne


My EP recommends that I take 200 mg CoQ10 daily.


Thanks for your reply djmnet. Are you taking Rivaroxaban?



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