What pain relieve can I take with Edoxaban

[Norfolk_spaniel]

I am 72 and had a successful ablation 2 years ago for persistent afib. Ever since then, my cardiologist has insisted that I stay on Edoxaban. I now have severe arthritis in my knee with considerable pain. I take 8 paracetamol a day which hardly touches the pain. I saw an orthopaedic surgeon yesterday who said that I should be taking anti-anti inflammatory for the pain and he would not contemplate any other treatment. My GP has always told me that I cannot take anti inflammatory with blood thinners. Anybody been in the same situation?

[Paulbounce]

Hi Norfolk.

Whatever you do, don't take ibuprofen. I was once told to take it by my GP instead of paracetamol. It's not the best of ideas if you have AFib.

Try CBD. It can be quite effective, but don't buy it from your chemist. They will be expensive ~ I can recommend a good platform to buy online. DM me if you want their details.

Rgds Paul

[Tapanac in reply to Paulbounce]

Would you mind telling me as well please about where to get CND Paul as my poor hubby suffers so much with his back which GP says is west and tear

Thank you

[Paulbounce in reply to Tapanac]

Hi Tapanac.

I can't find the company I used to order from as it's been a few years. However, I've done a little research online, and this lot looks good to me:

justcbdstore.uk/

So much so, I've just ordered some for myself. For £23, it sounds pretty good. I haven't used them in the past, so I can't give a personal recommendation, but they appear to be genuine enough. If not, I'll update the post.

Rgds Paul

[Tapanac in reply to Paulbounce]

Thank you Paul. Although my hubby is 83 he walks and feel much older and it’s all to do with his painful back

I can try him with these if there is no harm in him taking/using them

Pat

[Paulbounce in reply to Tapanac]

Hi Tapanac.

I don't think there will be a problem for one minute. Check with your doctor first but I'm sure it will be OK.

Best not to buy the 'full spectrum' as has this has a trace of THC in it.

Rgds Paul

[BenHall1]

I'm on Warfarin and use CoCodomol 30/500 ... only on prescription I'm afraid.

I used it pre and post knee replacement surgery. Very good.

[Cavalierrubie in reply to BenHall1]

I am on warfarin John and was told l could take Cocodamal. You can buy it over the counter, but it’s not so strong as a prescription from GP.

[BenHall1 in reply to Cavalierrubie]

Cavalierrubie ...... thats the one I'm on CoCodomol 30/500, only on prescription. Originally prescribed for osteoarthritis pain in knees. Now for osteoarthritis pain in both shoulders, left worse than the right. 😢😢

John

[Norfolk_spaniel in reply to BenHall1]

Thanks for the reply. I should have said that I can't tolerate cocodamal, it makes me vomit within 10 minutes of taking it.

[Cavalierrubie]

l would go back to your GP. There are other pain killers but also treatment for your knee would be a good idea. Pain killing injection into the knee could be given. You do have to be careful not to take anti inflammatory with blood thinners. You need some proper care so don’t suffer in silence. Good luck.

[Norfolk_spaniel in reply to Cavalierrubie]

Thanks for the reply. I had a cortisone injection in my knee on Thursday given by the consultant. I had great hopes from it but 2 days later there is no improvement. The consultant was so insistent that I should be on anti inflammatory and would not offer any treatment other than the injection.

[Cavalierrubie in reply to Norfolk_spaniel]

Sorry to hear the injection didn’t work. Don’t bother with the consultant, he does not know your medical history. See your GP for pain relief. He/she should be helping you with that. Taking 8 paracetamol a day. which isn’t working, is not doing you any good. There are alternatives you can take other than anti-inflammatory medication. I think you need to do some complaining here. Wishing you well.

[wilsond]

Your orthopaedic consultant is on my opinion an idiot! Putting it as mildly as possible,even my GP knows you cannot take anti inflammatory drugs with anticoagulants. Well known risk of gastrointestinal bleeding....says so on the the flaming leaflets!

I'm sorry,I'm in the same boat.

I can take co codamol,as a kind of last resort for a few days.Spinal issues,so no replacement ..huh.

Your best bet,apart from changing from your 'consultant ' is for knee replacement surely?

Really not good enough! I begin to wonder if we are better off going to a vet!

I can't tolerate codamol except if im at my wits end but have found Soluble paracetamol better.

Sending best wishes

[MaryCa in reply to wilsond]

Are you saying here that you have spinal issues and won't be given a knee replacement? I've had both hips done with bulging discs and stenosis and in my opinion a lot of my back pain was due to me being crooked while walking because of one hip and then ten years later the other hip. Sometimes doctors really don't get that living with pain is extremely life limiting and depressing

[wilsond in reply to MaryCa]

No sorry, I meant same problem I'm that I can't take anti inflammatory drugs.

[wilsond in reply to MaryCa]

Dr's really don't appreciate that 😒

[Peony4575]

Unless you are contemplating surgery, you need to see a Rheumatologist . They specialise in managing joint disease by non surgical methods and could recommend the appropriate pain relief to your GP . Their waiting lists are long so if you can afford the £200 ( approx) go privately . Your quality of life sounds like it is badly affected

[gstedders]

whilst I was waiting for a hip replacement the dr prescribed Meptazinol, Meptid short name. It worked well, it’s an opioid but not recommended long term.

[JOY2THEWORLD49]

Hi

Unfortunately an anti-inflammatory is NATS like ifroprofen and 100mg would do the trick.

It is a anti for pain in arthritis. I was given indosid in 1970s for period pain and if in my ststem before p.pain during the first 24 hrs I breezed through. He said 10% of population would be cured during this temporary state.

I am 76 years and I take the lowest dose of PRADAXA 110 twce a day.

I chose PRADAXA because 1/2ing the dose I felt better.. No large dose at once and it has an antidote.

Your cardiologist should have offered you codeine and paracetamol combination.

Sometimes GPs OK low dose of ifroprofen.

You can't live in pain. Either way you look at it Norfolk_spaniel.

I guess each of your specialists are flying the flag for your health but ultimately it is your QOLife.

Is there an arthritis specialist you can get a consult with.

Take care.

cheri JOY 76 (NZ)

[JOY2THEWORLD49]

Hi

I'm not sure who one can depend on.

Before my right shoulder surgery I asked my GP for pain relief for post surgery.

Lucky that I did because my Orthopaedic Surgeon was prescribing me a NATS and I said no I'm on back on my anti-co.angulant PRADAXA 110. My GP gave me a choice of tramadol and/or paracetamol. No way 8 a day - but 2 x 8 hrly day of paracetamol. I was able to wean me off within 2 days post operative.

Another operation Mesh removal done in Northshore Public Hospital gave me 3 days of OZI-NORM. I used it for the first day only. Of course like this one, is addictive. REmember though 3 times daily. My 21 year young counsin in Canada died of an overdose. So sad.

cheri JOY.

[Drone01]

Short of knee replacement surgery you might find that ibuprofen gel applied externally helps reduce the pain and is compatible with anticoagulants.

[hausjac]

Every six months my ortho surgeon arranges for me to have an injection of Durolane into my knee as well as steroids under ultrasound guidanc - that is important. Steroids alone won't do it. This is also known as hyaluronic acid and will help. Look it up on the net. Also you can take anti-inflammatories topically but obviously to get a stronger ointment you need a prescription for that.

[Norfolk_spaniel in reply to hausjac]

Thanks . I paid for a course of hyaluronic acid injections last year and they made the pain worse.

[CDreamer]

No to anti inflammatory meds with AF, never mind the Edoxaban. You could try the anti inflammatory gel or spray though, used sparingly that may help.

I use Resveratrol supplements (supplement high in poly phenols and made from purple foods - beetroot, red grape seeds etc) alongside 1mg/day of Glucosamine with MSM. It’s not immediate relief - you will need to take for at least a month but has worked well for me.

Also consider Acupunture for pain, worked for me when my pain got toward being intolerable- mine was in my feet.

Hope you find something.

[MaryCa]

Is he saying he won't do knee surgery?

Ok, you can not take anti inflammatory meds with a blood thinner, it's too dangerous. But ixprim, tramadol, palexia, solpadeinr, co-codamol could potentially all be taken, most on prescription. But obviously gp is well versed in your history so ask him for something stronger. People don't realise how depressing and life impacting pain can be.

[wilsond in reply to MaryCa]

But Co codamol only recommended for 3 days??

[Lakky12]

what reason has your consultant given you for not considering other treatments? Arthroscopy? Knee replacement? Have you had x rays done? If so and they show extensive arthritis I’d change consultants!

[Twosumsmum]

I take codrydamol for joint pain when it’s getting me down . That’s a mixture of paracetamol and DF118 . I can’t cope either codeine based drugs . But daily I take rosehip tablets and vitamin E , the rosehip helps the paracetamol and I’d a natural pain med with no known contraindications. And vitamin E acts as the magic anti inflammatory without upsetting the blood thinners I am on .

[ibuputih]

Hi - I really feel for you. Severe joint pain is horrid and wears you down. My second knee replacement is being done next month.

Your OS is not helping you with this. Steroid injections don’t always work, and when they do, there is no guarantee how long the relief period will be.

Unfortunately, it is not unusual to have to remind that Edoxaban precludes the use of ibuprofen - if it’s not in their field, they forget! But you should then be offered (the albeit limited) alternative options. Most importantly, if you are in constant pain, your knee should be properly assessed and a time plan for replacement suggested.

Paracetamol does very little for me and the codeine based tablets upset my stomach. This means having to rely on topical means to alleviate pain - which is not as simple or effective as just taking pain killers.

Ice helps hugely. Also a topical spray - Biofreeze - recommended by my physio. Exercises to enhance supportive leg muscles can also help. If it hurts at night, a very soft pillow under the leg can keep the knee still and less painful.

It’s worth bearing in mind that immediately post replacement surgery, all patients are given anti coagulation for a period of time to prevent clotting. Therefore, in those early post operative days, pain relief can only be paracetamol, codeine/co codamol/ co dydramol and opiates. It follows that a patient on permanent anti coagulation for AF, would have to be offered the same menu for pain relief pre- operatively.

[Norfolk_spaniel in reply to ibuputih]

Thanks for your reply and you have clearly understood my condition and my predicament. I can't take codeine as it upsets my stomach and i'I'm relying on Oramorph to control the pain although I hate the way it makes me feel. The consultant that I saw on Thursday was very rude, obviously hadn't read my notes and all he said and kept repeating was that I didn't need a knee replacement and should be taking anti inflammatory. When I pointed out that I was taking blood thinners, he just shrugged. I have already put in a complaint but that doesn't do anything to move me closer to treatment.

[ibuputih in reply to Norfolk_spaniel]

Oh dear - looks as though you have got ‘one of those’ consultants. Have you had X-rays/MRI?? If not, how can he possibly know what the state of your knee is and if you are a candidate for replacement? If your knee has been scanned and the level of wear/deterioration is not deemed to be suitable for replacement it could be something else (like a bursa) that’s causing the severe pain and that should be investigated and addressed.

Unfortunately it looks like your options are few. Given you have already made a complaint, could you follow that up with a request to see an alternative OS for a second opinion? Is your GP helpful? Could you speak to them and see if they could help? Any chance of just paying for a private consult to get a second opinion (although they’ll want to take scans etc which are £££). Finally, I have found pharmacists very helpful in drug related issues. Perhaps they could suggest a time or way of taking your medication that would make you feel better?

Really hope you can find a way to be in less pain and feel better.

[Norfolk_spaniel in reply to ibuputih]

Thanks for your reply. I had an xray a few weeks ago and the excellent lady at the muscoskeletal service said it would make the cartilage look a lot better as she thought I had a ruptured bakers cyst. The consultant was dismissive of this when I queried it and just said "it's arthritis ".

[wilsond in reply to Norfolk_spaniel]

He sounds a right arxxsole!!!!

[Birdsaplenty]

Hello, I'm 75 , Ablation X3 because of AF. .Had 3 spinal discs removed because of nursing when I was 57.I have to take Tramadol because of horrific pain. It's made life livable . No problems taking this. Nothing worse than constant pain. I feel for you. Hope you get relief from your pain Best wishes , Deborah

[Hollins]

Hi. I'm on an anticoagulant and have an arthritic knee.

Acupuncture works well for me . The effect lasts a few weeks. No problem with the needles, they're very thin.

As I understand it Acupuncture works for some people but not others. There'd be nothing to lose (except the fee!)

H

[Norfolk_spaniel in reply to Hollins]

Thanks for your reply. I had a course of acupuncture late last year. I really enjoyed it but it didn't help,

[Ellie-Ann]

yes. Told NO ibuprofen but paracetamol ok. Hope you find some relief soon.

[DawnTX]

hi there. Do not take ibuprofen as Paul mentioned take acetaminophen. I have had three different EP’s tell me this is OK. Also try to avoid. nsaids unless it is occasional best to stay off it though. I am also on tramadol and have been on it. I have a pacemaker now and had an AV node blockage done. I took the tramadol prior to and still have it monthly that I can refill and usually need to.

my pain is not anything to do with my heart. I was hit by an 18 wheeler over 12 years ago and I have chronic pain pretty much to as a result. I had several ablations done on different parts of my body, including my neck. Those areas are great, but I also have spinal stenosis and I have just been diagnosed with thyroid waiting to get all the info on that, but I’ve already been told it is capable of causing or increasing about a dozen different pain sites that I already hurt in. Good grief why can’t we get this when we can handle it better when we are younger?

I don’t know why he didn’t tell you acetaminophen. I would think he would prefer that over you taking what I would consider far too much of what you are using now. I take tramadol twice a day morning evening, and it gets me through the day, usually the anti-inflammatory part of acetaminophen. I seem to need some sometimes not all the time. I also have had a prescription for Celebrex because I had some type of an odd bursitis in my hip. My specialist gave me a shot not fun that was the worst part lol but when it hurts that much it usually means they got the right spot. Then he put me on one Celebrex a day for a month.

oh yes, I am on Xarelto my anticoagulant and I’m told it will be for life. Obviously, no one expects you to suffer from other pain the rest of your life because we are taking that.

i’m not sure I like your doctor. Tell him you need some quality of life. You’re not looking to be a drug addict. Tramadol is controlled. I must see my doctor once a month to get my refill because of state law other than that he’s not worried about me being a drug addict or hurting anything else in my body.

find someone that will listen to you about the pain. Do you have pain management doctors? At one time that was a bad word they used to hand out heavy medication without question. At least the ones here are very strict. My last one in Florida gave me a muscle relaxer once I never had any other kind of meds from him. He did my ablation on my neck an hour after it was done I was able to move my head again. I not been able to do that since the accident and had to turn my whole body backing up my car. They also believe in physical therapy, etc..

best of luck pain is exhausting and it’s pretty obvious what you are taking which I know is popular over there is not doing it for you. Stick up for yourself ask questions.

PS I just saw someone mentioning Biofreeze. I used to swear by that, but I just found something better and believe it or not less costly if you can get it. ASPERCREME puts out a spray now with 4% lidocaine in it. Oh my goodness it works fast. I have meralgia down my left side. Sometimes it says though someone poured boiling hot water or oil I could cry. It hurts so bad, especially standing up or sitting down.

We can get stronger lidocaine, but only by prescription 4% is the strongest whether a a cream or spray this is one of the few sprays that I found that has it Biofreeze has lidocaine

[Hallane]

Ibuprofen gel on the area would not increase the internal bleed risk associated with oral nsaids taken with anti coagulants.