Pluvicto and vomiting

[Gl448]

anyone else have that side effect?

I had my first injection exactly one week ago. I didn’t notice any side effects, but two days ago I had the dry heaves, and today a couple of full vomits. Funny that I had no food this morning and only cup of water for meds. Followed by some Pepto-Bismol, 1 hour later when it felt like heartburn. 5 minutes later vomiting.

Is 5-7 days since injection in the zone of normal? ChatGPT it should be just a few days.

Going to call the triage nurse and see if I can get some nausea meds.

[GP24]

Usually they give you nausea meds at the time you get the injection. It is a side effect of the Pluvicto therapy.

[Gl448 in reply to GP24]

Yeah they didn’t give me anything for it, I know it’s a listed side effect.

Just curious if others had had it and how long after injection.

Thanks

[GP24 in reply to Gl448]

I did not notice that I got it but I had constipation after the injection. Nausea for a week after the injection is a long period but I would not worry about it.

[SViking]

I did not experience nausea but for about a week after the shot, most food tasted poorly. And my hemoglobin plummeted to 9 and has never returned to normal, just fluctuating in the high tens.

[God_Loves_Me]

many people also reported extreme fatigue after 10 days.

[Gl448 in reply to God_Loves_Me]

Great, something to look forward to! Ugh.

[Bigdo58]

Enjoi! Its always better than the longrun alternative. I am hoping to get it in Australia, 60k I'm told, likely cost, if I can get access, 10k a shot. Hoping to sweet -talk a discount of some sort.

[spencoid2]

I have nausea often and am not really sure if Pluvicto increased it? When I have nausea or acid reflux I use a generic equivalent to Mylanta and find it is much better than Pepto which does pretty much nothing. The one I really liked was discontinued because it was killing people? That was Malox and I think it was some QC issue not that the stuff was always bad. Too bad because it really worked. I still have a few tablets and little plastic containers of it that you could get in Europe but not here, in reserve for "emergencies"

[Gl448 in reply to spencoid2]

Maalox was always my favorite for dealing with heartburn.

[OldWarrior]

i’ve had two cycles of Pluvicto - vomited once each cycle, both times within 48 hours. Hemoglobin and platelets both low - third cycle delayed as a result.

[Apd66]

I had nausea and vomiting after pluvicto. Would last about 5 days after each dose. Anti nausea injection prior to pluvicto helped tremendously.

[God_Loves_Me]

may be time for prescriptions of 25MG Zofran Medication

[countrymusic101]

Get checked out and follow up with your medical team. I received three injections 4 and 6 weeks apart and they also gave me nausea medication intravenously. Never had any issues each treatment.

[Histbuff]

My docs gave me Zofran but I have found that for light nausea Ginger Ale works well. So do chewing ginger gummies.

[carguy]

I just completed my 4th dose of Pluvicto and was nauseous for a week after each dose. The third dose was the worst, was nauseous for 2 weeks after and had dry heaves the fist 2 days. I got a prescription for generic Zofran which helps. I also found that Enterade (2 bottles per day before meals) helps protect the lining if the stomach and reduces nausea. Enterade also helped reduce nausea during chemo.

[Gl448 in reply to carguy]

I found a bottle of Compazine from my chemo last year; I never really needed it for chemo, but I took a couple for this recent belt of vomiting and nausea, and it did OK.