Janux immunotherapy drug (JANX007) for mCRPC

[nyc_son]

Are folks familiar with this treatment, JANX007? If something like this were rolled out, how widespread could it be given? I'm not very familiar with immunotherapy treatments.

investors.januxrx.com/inves...

"Analysts were particularly impressed by the results Janux shared from treated participants with metastatic, castration-resistant prostate cancer..."

biopharmadive.com/news/janu...

[Tall_Allen]

Lots of BiTES in clinical trials.

[nyc_son in reply to Tall_Allen]

Do these require you to test positive for certain genetic traits? I was reading posts from a user who reported being in this trial and it didn't sound like they had such markers.

[Tall_Allen in reply to nyc_son]

No. They target surface proteins, not genetic markers.

[nyc_son in reply to Tall_Allen]

Promising... in theory.

[Tall_Allen in reply to nyc_son]

Right. So far, no BiTEs have made it to Phase 3 trials for PCa. It will take many years.

[j-o-h-n]

So far Keytruda is a winner....... for my Melanoma metastasis to my lungs....

Good Luck, Good Health and Good Humor.

j-o-h-n

[nyc_son in reply to j-o-h-n]

I'm glad to hear. That requires certain genetic testing, correct?

[j-o-h-n in reply to nyc_son]

I wish I could answer that........ but all of that was left up to my Lung/Dermatologist Oncologist at MSK..... Docs get the big bucks....

Good Luck, Good Health and Good Humor.

j-o-h-n

[Hotrod65]

MPC4..small cell Neuroendocrine, going on 10.4 years after treatment with PD1 Immune Checkpoint inhibitors immunotherapy Keytruda.., yes, required both zGenetic and Genomic Sequencing thru Foundation Medicine to determine my qualifications?.