post prostatectomy psa

[Elkguide]

hello. I Had surgery June 13 2023 biopsy showed Gleason 8. Psa 13 perineal invasion seminal vesicle invasion post surgery pathology Gleason 7. First two ultra sensitive psa came back with less than symbol 0.02. Then my last ultra sensitive psa came back 0.02 without the less than symbol. Is this something I need to be concerned about. I am just seeing the urologist that did surgery. Should I get a med. Oncologist onboard. Age 71 thanks in advance

[Tall_Allen]

No need to do anything unless PSA reaches 0.1 or 0.2 if it ever does.

[Elkguide in reply to Tall_Allen]

Thank you so much. This journey can be very difficult it’s good to know there are people who care. Thanks for you reply I read a lot of your comments

[GMorz]

Mine was the same . After RP was 0.014 then 0.010 then 0.013 then 0.020 then 0.023 then 0.020 26 months post RP. Hopefully stays where it is . Nice if was 0 but as long as stays where it is. Listen to Tall Allen he has been amazing support and source of information to keep all in perspective.

All the best with your journey

[Justfor_]

The first reliable landmark is 0.06 which is considered the pivotal point ( i.e. 50-50% probability) of an impending BCR. Until then, just monitor.

[tn12 in reply to Justfor_]

Hi Justfor_ you have similar pathology to my husband. He went from 0.01, 0.02, 0.03, 0.02, 0.04 now 24 months post RP. Do you have a link to refer to the 0.06 point? Thanks

[Justfor_ in reply to tn12]

Excerpt from:

"Optimal definition of biochemical recurrence after radical prostatectomy depends on pathologic risk factors: identifying candidates for early salvage therapy" (2014).

pubmed.ncbi.nlm.nih.gov/240...

A 0.05 followed by a 0.06 is the earliest pivot for a 5-year BCRFS from <50% to 50-75%

[tn12 in reply to Justfor_]

Thanks. I'm confused where it says prob is >90% for progression free if PSA is >0.4? Isn't PSA 0.4 not good?

[Justfor_ in reply to tn12]

For some, unknown to me reason, the site refuses to copy-paste the original text in its entirety. It skips a part of it, completely changing the meaning. For this reason, after many unsuccesful tries, I ended up posting a screenshot.

[MNFarmBoy]

It is entirely possible that the "<" symbol was somehow left off the transmitted result, whether entered by a human being or via an automated system.

[Elkguide in reply to MNFarmBoy]

thanks to all who replied. When I went in for office visit with urologist he started with worse case scenario and said nothing about that it is still undetectable. Needless to say I wasn’t in a good place after leaving. Thanks again everyone not sure what I would do without your help and support

[markprince]

I am a patient at MD Anderson and they won't test at less than 0.1. IOW , everything below 0.1 is noise. Right or wrong its part of their SOC. I wouldn't want to fret over such small changes anyway. After the prostatectomy mine went straight to 0.3 within a few months but I knew that was coming based on the post operative pathology report. Then did SRT / 6 mos Lupron. Last radiation treatment was 6/19/23. testing every 12 weeks and still <0.1.

[Elkguide in reply to markprince]

Thanks markprince

[j-o-h-n]

"0.02" is like hitting the lotto.......

p.s. Good idea to fill in your bio...........

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 01/18/2024 11:14 AM EST

[Elkguide]

thanks j-o-h-n. Just did. Got her did