Hello everyone and thank you for this wonderful community for giving me so many resources.
My dad was initially diagnosed at a very high PSA of 3103 and he is doing triplet therapy, he is about to take his fifth docetaxel chemo dose and it seems to have stabilized to 99.30. He has bone metastases since diagnosis (+ one that gives him pain to his right hip)
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PSA Nov.11/22: 3103
Given Firmagon on Dec.2/22 (240mg)
PSA Dec.28/22: 500
PSA Jan.24/23 : 600
Given Zytiga to take the same day after blood test
PSA Feb.02: 356
Started Docetaxel on Feb.02
Before second dose: PSA Feb.27: 121
Before third dose: PSA Mar.20: 99.30
Before fourth dose: PSA Apr.11: 99.70
We are at the third dose of chemo
Before fifth dose: PSA May.2: 99.30
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He is going for six doses as is SOC. I was scared that it was increasing as per my last thread but my oncologist told us to keep the chemo going for now and watch out for any changes, and for now it seems to have stabilized. He has a triplet therapy of Degarelix, Zytiga and Docetaxel, but he can't stand the pain of monthly degarelix injections so he's gonna switch to Tritptorelin every 3 months.
I read that <1 PSA is the optimal point to reach, but also I know I can't ask for the sky when the initial PSA was so high. I know a fall of 97% is great news, but I wonder what this community thinks about it.
Should we seek additional treatment, if available, to make it go even lower, or should we just take a wait and see approach until it starts increasing again? Thank you.