I had my last Lupron injection 6/14/22 after 18 months of ADT and Radiation. PSA at the end of December was <.03 and testosterone was<3. My question is can I expect to return any time soon?
My age is 75 and I am physically fit I am doing 5 or 6 miles walking everyday. Do they ever boost ones testosterone after all this?
I’ve been on 2 vacations. Both times it took between 4 and 8 months for my T level to start to come back. At 4 months it was still at a castrate level and at my next appt at 8 months it was back in the normal range. Actually it was in the high side of normal. Since I had no baseline T level taken prior to ADT I don’t know how it compared to my pre-ADT level.
Sometimes T never returns. Clomid or HCG can encourage natural production. After 2 years of low PSA, my urologist was willing to prescribe testosterone for me.
TA, does that mean you were on ADT for two years and then opted to take a vacation?
I was never on ADT. I just had low T.
Thanks. I kind of thought that was the case.
I was 50 at diagnosis, baseline T was 395. 26 months of Lupron+ apalutimide finished last April. 7/22 it was back up to 285, 11/22 611, and 2/23 903. I haven’t done anything to supplement or otherwise juice my T. Just kept my physical fitness routine of walking 5 miles a day and lifting weights twice a week. So yeah, it can come back.
Here's my clinical history. Last Lupron shot March 2018, by October, T was 135, by February, 482. I did follow my normal exercise routine, elliptical, indoor bike, weights, swimming, outdoor biking, lifting weights, playing basketball, may have been a factor in my T's return.
Kevin
I am having AVEED testestorone injections with my urologist and am feeling great Acting like a 16 YO in bed
LOL. Brilliant
I have had Cypionate injections since 2016 bringing my *T* to 1,600ng/dL following the injection with very little noticeable results BUT then I am a Certified NN individual. NN = No Nuts = Castration in 2015
Sometimes T never comes back. Lupron/Eligard from May 2003 to February 2010 with a six month chemotherapy trial with ADT in 2004. MO had be stop hormones injections. When T did not come back in January 2011, he had me start topical testosterone. I remained on that until December 2021. T ranged from 350 to 700 depending on when I applied the gel and when I had PSA tests (every quarter). Without the added T, my T level is consistently 23. I maintained undetectable PSA from October 2006 until August 2021.
GD
How's PSA now?
that in its self is interesting.... first of September 2022, I started with gross hematura with blood clots. PSA jumped to 0.3, then 0.57, then 1.7, then 4.0 and back in 0.2 in January. In between a raging UTI while traveling to Greece on December 1, 2022. In the interval I have had a cystoscope, Urogram, PSMA PET, Nuclear Bone Scan (my 27th), Peivic MRI with Prostate Protocol. All negative for Prostate Cancer. Given a very enlarged prostate, out of whack parathyroid test (1x), and UTI, both my Professor of Genitourinary Diseases Medical Oncologist and Urologist both agree, given my 20 year history, BPH.
I wish you well. Everyone is different in scope of disease. Just think, I had two spinal Mets in 2004.....
GD
Yes, your story is a continuing inspiration.
I had prostate removed, went through radiation, and was on Lupron for 20 months.
It took 2 years to get my T levels up. It took quite some time before any real rise (6-9 months), but they kept rising slowly for quite a while, then ramped up a bit over the last 6 months. They check my PSA and T levels every 3 months.
The walking is great but do you lift weights? It helps T to return and At 75 you should be anyway.
I took HCG to stimulate natural production on my way back but that is not for everyone. Resistance training is.
I posted about no baseline T level being noted at the start of my ADT. After I stopped it after my initial 3-month injection I continued to have severe side effects (not "normally' common but I suspect was present and not reported - depression) for 11 months. I considered asking for T shots to bump it up during that really horrible experience. I would have traded off an increase in my PSA and presumably my cancer growth just to get my QOL back to a tolerable level. I missed a year of my life in bed with not motivation and more serious issues.
By the way, my PSA last week was 19.7 and steadily increasing. SOC does not allow any other therapy other than ADT until castration resistance is documented. Chemo can be if desired, and ultimately radiation as a palliative therapy for bone pain. My MO, this week, suggested I go to a 6-week cycle to check my PSA and get additional CT and bone scans if I experience bone pain or my PSA shoots up much more. My scans last week showed only minor possible PCa growth. My PSMA-PET scan showed definite and wide spread lymph node involvement but this was not picked up to a very significant degree with my recent CT and bone scans. There were indications that it will show up in the short term rather than long term, hence the PSA checks/new scans more often. I can't wait - LOL.
I was also on Lupron for 18 months and ended Proton Radiation in October of 2020 after Gleason 9 PCA. Now My PSA is 0.4 and my T is 704. I am 79 and usually walk a half-hour each day.
I'm just slightly younger than you, had 13 months of ADT (Eliigard) for localized high risk PC, T was below 10 during treatment (IMRT and LDBrachy), and it took about 3 months for my T to bounce back to almost 600 after stopping the hormone shots. My T kept going up to almost 800 after that, but has since dropped off to about 350 for some unknown reason, and I can definitely feel the difference. I'll probably discuss it with my family doc next month, but I'm a little hesitant at this point in poking the bear (PC) by artificially increasing my T, since it's only been about a year since ending treatment for this charming disease and I am still closely monitoring my PSA. 🦊
After 9 months worth of Lupron, it took a year for my T to return to the normal range.
My comment is, that you "Test your own" and I'll "Test my own"...
(Beware the ides of March).
Good Luck, Good Health and Good Humor.
j-o-h-n Wednesday 03/15/ 2023 11:07 PM DST
No one can answer that question. Keep doing what you're doing and hope for the best.
Testosterone increase after injection
Testosterone and Lupron
Why is Testosterone Increasing?
Testosterone injections.
Testosterone levels !!
