Testosterone and Lupron

[Craigslife]

My husbands oncologist wants my husband to get back on Lupron. DH’s testosterone is 1.2. Is there any benefit to Lupron when your testosterone is already so low? Right now he is on olaparib and scheduled to begin Keytruda in six weeks.

[Tall_Allen]

What are the units - nmol/l or ng/dl? If nmol/l ( which I think it is), it is 35 ng/dl which is not so low.

[Craigslife in reply to Tall_Allen]

I just checked...nmol/l.

[JLS1 in reply to Craigslife]

Adding Zytiga might help to lower testosterone, if that's what your Dr is trying to do. (What our PC specialist did a few months ago) I wonder if your husband can try Zytiga again. There are clinical trials now of olaparib with Zytiga.

[Craigslife in reply to Tall_Allen]

I had no idea there was a difference. Thank you for your response. I intend to read more about this. I did read that testosterone should be < 50 ng/dL.

[Tall_Allen in reply to Craigslife]

50 ng/ml is a minimum for castration. Most doctors would like to see it below 20 ng/ml.

[Craigslife in reply to Tall_Allen]

Thanks, I will share that information with my husband.

[Hidden in reply to Tall_Allen]

I'm not aware of data to support this but it seems to me that even lower is better. But I don't know if a tiny amount of T is needed by the body.

[JLS1]

Did your Dr say anything about early olaparib plus keytruda clinical trial results? I've been wondering if this might be a good next step plan for my husband. I hope the olaparib is still working well.

[Craigslife in reply to JLS1]

His doctor plans to keep him on olaparib and add Keytruda.

[JoelT]

Yes there isJoel

[charlesmeyers1964]

what i would do is this. have has doc check his testosterone and see what his level is. mine was a 3 for about 8 months then we checked it and it was up. docs don't always check the level and i would. remember males has it from 300-600 if ones level is 3 then i personality wouldn't do it. i found the shot painful and with the low number felt it not necessary to continue for ever. remember it reduces ones bone mass, makes u tired and weak

[Marshb52]

Also on Lupron and I lift 3 days a week and cardio 3 I have fatigue and weakness with hot flashes with weight gain. I’m concerned about testicular atrophy. Use it or loose it. I’m going on a Lupron vacation after 7 mos of undetectable and hope things come back.