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Advanced Prostate Cancer

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Free testosterone

bitittle profile image
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See my profile for more details on history. G9 RP 10/2013, PSA rose again over 2.5 yrs. SRT to prostate bed only. Radiation completed 8/15/16. PSA slowly rising again over the last 6 years. Last quarter PSA jumped from 0.236 to 0.364. No ADT throughout my entire PCA history. My Radiologist has asked for Free testosterone tests the last 3 quarters. Not sure why? My Free Testosterone has increased from 8.0, 8.1 and 9.5(last quarter). I have an appointment with my Radiologist end of January to discuss PSA rise. I assume in the very near future will be a PSMA PET scan once PSA is high enough. I realize I have a BCR with 3 PSA tests over 0.2. What is the significance of testing Free Testosterone?

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bitittle
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Tall_Allen profile image
Tall_Allen

Unless your testosterone is unusually complexed with SHBG, there is no significance.

bitittle profile image
bitittle in reply to Tall_Allen

Thank you, Allen! I was hoping you would provide insight!

Ralph1966 profile image
Ralph1966

Hi,

May I ask your Total Testosterone level? You said that you never got Lupron injections right? So I assume that your Testosterone level is normal or even high?

bitittle profile image
bitittle in reply to Ralph1966

My testosterone typically runs in the high 300's around 380 +/-. This quarters test results total testosterone was 311. Due to extensive travel, I was lucky to get in 5 miles a week of running in comparison to my average 20-mile week.

GeorgeGlass profile image
GeorgeGlass

Here's how it is significant. It's a predictor of outcomes. It's good to keep it low. spandidos-publications.com/...

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