Graybosch cautioned that other experimental cancer drugs showed promise in Phase 2 studies only to disappoint in Phase 3.
Brad Loncar, a biotech investor who runs an exchange-traded fund tracking immuno-oncology companies, told Insider that Moderna made a good decision in focusing on a narrower patient group who had surgery to remove their cancer first. But Loncar added other types of cancer are harder to treat than melanoma, which he called a "low-hanging fruit" for immunotherapies.
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but everyone on earth is going to die. I am not arguing, just trying to learn. The question is when? If you are stage 4, and your psa is still undetectable for 5 years, then it might take another 10 or 15 years to the end. I am not sure how to see this situation.
there are several long term survivors on this group that have stage IV. Im not giving up that easy! I know it is inevitable that I will become resistant if I can’t get a handle on stopping cancer stem cells or alpha keto reductase or the glucocorticoid receptor resistant pathways…. Im also seriously working on doing a modified BAT , but i tell ya i ain’t giving up!
Have you ever tried taking Dandelion root powder mixed in your tea cup I stumbled on this remedy recently so I bought 100 grams of it & im taking two level tea spoons once a day as I have severe Prostittis & within hrs the pain subsided in my prostate & after 3 days I’m cutting down on pain killers, you see there are natural remedies all around us & Dandelion has a unbelievable 17 compounds it’s one of the most remarkable plants for its size & it reduces fluid retention in my legs & yesterday I was able to miss taking Tamulosin a prostate prescription drug to shrink the prostate, so I read a few weeks ago Dandelion root has anti cancer capability’s so I thought you may want to give this plant a try
interesting, Daleboy, thank you! A delicious tea, sweet tasting is SOURSOP leaves. You crunch up the DRIED leaves and let boil lightly for about 20 minutes. You can make extra to have more then one cup. The leaves will just sit at the bottom of the kettle, they won’t get into your tea. Smells so good too!
not necessarily. Majority of stage 4 guys are old enough to die from something else. Not sure that’s helpful but it is pretty slow compared to heart disease/stroke if you are in your 70s plus. That’s my hope.
"In this cohort study of 26 168 patients with metastatic PC, 16 732 died during the follow-up period. Of these deaths, 77.8% were from PC, 5.5% were from other cancers, and 16.7% were from noncancer causes, including cardiovascular diseases, chronic obstructive pulmonary disease, and cerebrovascular diseases."
Those who have had successful local treatment to the prostate and no recurrence are more likely to die from something else.
well that pops my bubble. you would think we would have a handbook on how to live with this stuff to survive the longest. Or don’t they really have any ideas to put in a book.
REMINDER: Please keep the conversation civil. Skepticism leads to pessimism...that's ok, but let's not jump on each other because of expressions of hope or fear.
I was diagnosed stage IV in 2014 at 54 years old with distant bone Mets and lymph nodes. I’ve had many of the treatments available to date. Had radiation in 3 bone Mets a week ago. Will probably need Pluvicto in the next 6 months or so but so far have had a great life while being treated so I wouldn’t consider aStage IV diagnosis as a quick death threat.
The disconnect with reality here is due to the fact that most people on this forum don't have APC. Don't know why they are here other than tell us things like we need to drink dandelion tea.
Hi Ed, there are a lot of stages of advanced prostate cancer. Many of us are stage IV with mets elsewhere but are still hormone sensitive, and have the time if you will to try many supplements, repurposed drugs like statins, SARMs and even herbals. Unfortunately there are to many of our fellow warriors like yourself that are castrate resistant and running out of options. My heart goes out to you guys and I try to read all your posts because us slightly advanced warriors need your knowledge. So don’t get upset over n=1 remedies as they are only trying to help. If someone has tried a natural product and it worked for them they should share this information. It is up to everyone to do their own research and decide for themselves whether to disregard or not.
I’ve had this crap for 4 years and you just taught me something new. I always thought that if you had Mets you were CRPC. good to know that is not true. So now I wonder what causes the CRPC?
Onset of CRPC is established in the current scientific environment by confirmation of biochemical and/or radiologic progression (detected by rising prostate-specific antigen [PSA] levels or imaging, respectively) with serum testosterone (T) at or below historical castrate level (50 ng/dL).
We were in the Lake Louise area (Canadian Rockies) this June and watched in awe as two huge black bears heartily gorged themselves for some time on dandelions. I can share cell phone snaps to prove it. They were recently out of hibernation. Possibly some positive healthful effects for us humans.
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