Oral Hygiene and Zometa, Nubeqa, etc.

[Silentio]

At my Oncology Day Clinic, I was given Mycostatin (oral drops for fungal infections [thrush] of the mouth), and bioXtra (mouthwash for dry mouth). I have not been able to find any recommendations online regarding the need to use these agents after t having the Zometa infusion or taking the Nubeqa tablets. I was also given Pantoprazole which reduces the amount of acid your stomach makes and Valoid for nausea. At this point after one month on Nubeqa and one Zometa infusion, I have no nausea or any oral issues.

I was wondering if anyone else on Zometa, Nubeqa, Enzalutamide, etc. is taking these types of medicines for oral hygiene or gastrointestinal issues. Are they recommended as prevention?

Thanks.

[Tall_Allen]

I have not heard that oral fungal infections or excess acid were side effects of those drugs. Where did you hear that?

[Silentio in reply to Tall_Allen]

Thanks for responding. My hospital’s Oncology Day Clinic which is administering the Zometa and watching my bloods for the Nubeqa recommended the oral hygiene agents. I have not found any other mention of their use either.

[dentaltwin in reply to Tall_Allen]

Neither have I. But oral fungal infections (primarily C. albicans) are exceptionally common in the general population.

[tango65]

One should be sure the teeth are OK before having zometa or denusamb.

Infection, extractions and other dental surgical procedures are the ones associated with osteonecrosis of the jaw when taking these drugs.

If your teeth are fine, I do not see the need for anti acid reflux or superficial fungal infecciones medications.

[Silentio in reply to tango65]

yes, thank you for that. I did have my dentist OK the start of the Zometa. Many thanks.

[dhccpa in reply to tango65]

can one have crowns or bridges put in if taking denosumab? If so, what needs to be checked out?

[tango65 in reply to dhccpa]

Yes, if the bridge does not involve extracting a tooth.

[dhccpa in reply to tango65]

thanks. I'll find out soon. I'm skipping the 3-month denosumab shot at end of September while I begin the process with the dental specialist.

[tango65 in reply to dhccpa]

I believe extractions, and other procedures have a higher risk of osteonecrosis, it does not mean any of the procedures automatically end up in osteonecrosis.

[dhccpa in reply to tango65]

got it. Yes, a lot of uncertainty in my mind. But I don't think there's a super urgency, but needs to be resolved.

[dentaltwin in reply to dhccpa]

Some dentists may be leery. It is not unusual to come very near or contact bone in the course of preparing and impressioning teeth for crowns and/ or bridges. Generally though I agree that the risks are low compared with extractions (or periodontal surgery, placement of implants, or other procedures in which bone is directly or indirectly involved).

[dhccpa in reply to dentaltwin]

thanks

[Hidden in reply to tango65]

totally agree with tango. Take good care of your mouth, never go to bed without using your water pick brushing and flossing. Also, you can use Braggs ACV very diluted with water, to gargle.