PSA rise

[spencoid2]

I just got the results of a PSA test today. I am including PSA over time for reference. I am taking aberaterone 250 mg x 4 daily. I was expecting that after orchiectomy the PSA would continue to decrease. I know that castrate resistance is indicated only after three consecutive rises in PSA.

Is this recent rise over a little less than two months something to be concerned about? Should I just relax and see what the next one is?

1/20/2022 3.35 Today

11/12/2021 2.85 first psa after orchiectomy done on 10/19/2021

9/9/2021 3,36

8/16/2021 4.91

6/25/2021 12.72

4/27/2021 12.26

3/25/2021 13.23

3/8/2021 14.97

12/21/2021 11.1 after Firmagon and Zytiga

10/28/2020 110.06

8/11/2020 101.54

[Magnus1964]

Failure of abiratorone is not an indication of castrate resistance. There are other ADT drugs that may still work, i.e. xtandi, amplitude, etc.

[spencoid2 in reply to Magnus1964]

So maybe I should do another PSA in a month or two and then ask MO about changing drugs if it goes up?

[CAMPSOUPS in reply to spencoid2]

Well again I would rather see those here with more knowledge comment but yes at the least get another PSA test in 1 month I would think.Also how did the other blood markers/numbers in your blood test look aside from PSA?

When is your next appointment with your Dr.?

If it is within a month then probably it is ok to wait until then to discuss this with him or her.

[spencoid2 in reply to CAMPSOUPS]

all blood levels are either OK or not too far off the accepted range. ALP has been going up and down but nothing that looks horrible. Do not have another apt with MO scheduled probably should make one, it has been a while. Was getting Firm is Gone shots every month and MO visit maybe every 3 months. Has been 3 months and was probably zoomed.

[CAMPSOUPS in reply to spencoid2]

Firm is Gone shots. That's a good one!

I am a blubbery smooth skinned guy myself. ha.

[Magnus1964 in reply to spencoid2]

That might be what I would do. The rise in PSA may be due to the orchiectomy. The dying cancer cells are giving off PSA. You might find your PSA is lower.

[CAMPSOUPS]

You've been here awhile and I have appreciated your posts and replies.No offense or critique intended but it would be nice to have your bio on your "home page".

You know. The thing J-O-H-N always alerts members to lol.

Are you still taking magnesium. I could be wrong but I thought I read it can affect PSA.

How do the other blood markers look?

If I look at the PSA right before Orchiectomy and the PSA most recent (not the PSA right after orchiectomy) the number is similar. Could this be where your PSA is going to settle ?

Smarter heads prevail here so hopefully you will get some better feedback than what I offer.

[spencoid2 in reply to CAMPSOUPS]

Will try to figure out how to update profile. I thought I did that long ago but must have not.

[spencoid2 in reply to CAMPSOUPS]

Do not see where bio goes on home page or exacdtly where the home page is. Did edit profile a little but not much there.

[CAMPSOUPS in reply to spencoid2]

Well thank you. I'm not very digitally inclined so definitely dont or didnt mean to push you.

[j-o-h-n in reply to spencoid2]

to spencoid2,

Click on your avatar (the blueberries) and go to your site, click again on your avatar (blueberries) and a screen will appear which says "edit profile" in a box on the right side of the screen. Click on that edit box and proceed to either write your bio or cut and paste your bio from one of your posts.... If this doesn't work I'll return your payment as a full refund....

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 01/22/2022 5:00 PM EST

[spencoid2 in reply to j-o-h-n]

I think there is a little more there now A challenge with my very very very slooooooow Viasat "high speed internet"

[j-o-h-n in reply to spencoid2]

Looks good........... also wonderful looking dogs.....

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 01/22/2022 6:33 PM EST

[spencoid2 in reply to j-o-h-n]

Dogs? That's me and my husband

[j-o-h-n in reply to spencoid2]

hahaaahahhahahahahahahahahah Now that's my kind of humor..... THANK YOU...

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 01/22/2022 9:35 PM EST

[tango65]

Your PSA is stable at 3 if you round the numbers since 9/9/21.. In clinical trials I participated they rounded the PSA numbers and they did not use decimals. You have to take in considerations the error of the techniques used in measuring the PSA.

[spencoid2 in reply to tango65]

people on this group freak out if they go from .01 to .011 i did not think it was a big change but thought it should be going down not up. not real concerned.

[tango65 in reply to spencoid2]

It is not going up, it is stable at a low value which is good thing. Nothing to worry about.

[spencoid2 in reply to tango65]

great, I'll find something else to worry about

[j-o-h-n in reply to spencoid2]

Guy says to his girlfriend:

I often worry about my attention span.

But never for long.

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 01/22/2022 5:10 PM EST

[Hidden]

I think it’s a temp blip ,and hopefully it will zoom down to zero . But who’s kidding who .? Any uptick and we freak out a bit . Stay the course ! How do you feel?

[spencoid2 in reply to Hidden]

feel pretty good, getting used to being a weakling and the hot flashes etc.

[Hidden in reply to spencoid2]

Par for the course amigo! Keep your head up! 🤙🏽😎 keep rowing 🚣‍♀️