I saw a video where a holistic dr. mention that eating organic home cooked tomato sauce 3 to 4 times a week ,can prevent prostate cancer by %50, I would think those with mestastic prostate cancer can still help them along with what your doing like , radiation, surgery, and ADT. can't hurt because it is food.
Tomato sauce contains lycopene. It's a very good ingredient for Pca, one of many. You can buy lycopene as a supplement in pill form. But the sauce is a better way to go for absorption.
I think the best is cooking the organic tomatoes, yes a can of organic cooked tomatoes would probably work and I do take lycopene supplements, I wish I could cook my own organic tomatoes but I get heartburn from the meal. I just think cooking it myself ikwould be the best way and dealing with cancer , it really is not a big deal to cook them myself. just saying.
As addicted2cycling said, I too buy an organic paste in glass jars rather than try to make a sauce. You didn't supply a link to the holistic doctor's video. A 50% reduction of prostate cancers for those that eat a home cooked, organic tomato sauce, three to four times a week seems optimistic. A stand alone food? Synergy between foods, spices, supplements and meds can be very effective.
The video is on youtube ,Mark Hyman's talk show with Dr. william Li. the episode is called " Eat This to Starve Cancer & Prevent Disease., I know it says Prevent Disease but I have read a lot, dealing with PC and Lycopene and about eating cooked tomatoes
I just watched a video yesterday from Mark Moyad, MD, speaking to physicians on Grand Rounds in Urology. My understanding is he thinks the studies show it is a healthy diet not just the lycopene that is effective.
Synergy between foods, supplements. spices, and meds is powerful. An analogy--Army, Navy, Air Force, Marines, Coast Guard and the branches within each service.
If you are going into battle, bring the troops--all of them!
There is a PDF on line by one of the guv acronym agencies which says that condensed tomato or lycopene coupled with cayenne increases it's effectiveness. I have posted the link in response to others before.
Dr. Klotz was involved in the study about cayenne pepper where men with prostate cancers were given --I believe a 40,000 heat unit capsule AM and PM. It was found to kill cancer stem cells. Dr. Klotz was first interested in capsaicin when a patient of his who was hormone resistant stabilized his PSA by dosing himself 3X daily with hot sauce. Dr. Klotz speaks of this at a conference and has a graph of the patient's PSA. There is a video in which Dr. Klotz mentions this as well as other meds and foods.
I am short on time today. The PDF and video aren't difficult to find.
The studies used measurable amounts of capsaicin. I make a vegan, sweat off the top of your head chili, that I don't count as part of the capsaicin supp but if eaten near the end of day I do count the amount of lycopene from the condensed tomato products in the chili.
I take two 40k capsules a day and usually eat 3 hot peppers with lunch...well see if it helps with a durable remission. I did read a few anecdotal articles regarding capsaicin and prostate cancer and I emphasize anecdotal. In the end I love hot peppers my favorite being the serrano followed by the cayenne. I eat the serranos raw in my salads. The cayenne I sautee in extra virgin olive oil and the jar with my own tomato sauce. Living near Philadelphia, I have access to very good Italian steak rolls. I put about 10 peppers with provolone cheese on a half roll. Not for everyone but for me it's heaven.
The word "anecdotal" in your response to me is misleading. There have have been studies done and funded by the guv acronym agencies. I mentioned that to Nal. pjoshea13 posted a link to a study in which one of the doctors overseeing it was Dr. Klotz.
I have a busy day in front of me. Here is a link--and remember synergy is powerful. One food, supplement, spice or med alone doesn't have the effectiveness of a combination. The "Blue Zones" are an example of synergy in all things.
When I read study abstracts well sprinkled with "could", "may", "possible", "suggested" I need to read other studies with stronger qualifiers. I also look for references to other studies that either this study is building upon or this study is referenced.
For me, and ONLY me, I require scientific studies that are repeatable, otherwise I consider the observations ie. "anecdotal" ie...observational but not proven with repeatable scientific studies. Might be more lose definition of anecdotal but I think it can be sued nontheless.
I will end that I take capsaicin daily via capsules and peppers because, for me, there is anecdotal evidence it helps. I enjoy eating hot peppers so it's a win win IMHO.
My brother is one of the contributors to this study on PUB MED, If you want to know which contributor send me an Chat.
Notice the language difference to the study on capsaicin. This study is making a statement where the other is making an opinion...a big difference wouldn't you agree?
Capsaicin has been shown to alter the expression of several genes involved in cancer cell survival, growth arrest, angiogenesis and metastasis. Recently, many research groups, including ours, found that capsaicin targets multiple signaling pathways, oncogenes and tumor-suppressor genes in various types of cancer models.
Author: Ruth Clark, Seong-Ho Lee
Cited by: 230
Publish Year: 2016
Anticancer Properties of Capsaicin Against Human Cancer
pubmed.ncbi.nlm.nih.gov/26976969/
pubmed.ncbi.nlm.nih.gov/26976969/
There are pages of studies dating back to 2010. Dr. Klotz was involved a recent study. Dr. Klotz has an international reputation and at his suggestion, Gleason grades 2 through 5 were dropped as there is little difference between them and a Gleason grade 6. He is highly respected.
Are there any studies conducted on men with prostate cancer that show capsaicin actually inhibits prostate cancer...I know there is one article regarding a man who ate hot peppers and showed a reduction in PSA (anecdotal) but I have not come across any others...a search of Dr. Klotz on pubmed shows a study involving TRAMP mice or mouse...not sure how many of these critters are used but again...that is a mouse study and the findings cannot be extrapolated to men.
In my opinion....until there are studies involving men with prostate cancer....these findings are anecdotal.. We can agree to disagree...or no?
Capsaicin suppressed activity of prostate cancer stem cells by inhibition of Wnt/β-catenin pathway
Excerpts:
Studies have shown that capsaicin exerted inhibitory effect on prostate cancer cells, however, the effects of capsaicin on prostate CSCs remain undefined. In the present study, we showed that capsaicin could downregulate prostate CSCs markers and inhibit the growth of PC-3 and DU145 prostate cancer stem cells.
Findings from this study reveals for the first time the potential role and mechanisms of capsaicin on prostate cancer stem cells.
Anecdotal would mean that there has been NO research to find facts. The definition is what it is. No studies to base statements or facts on which is certainly not the case as screens of studies over the years have been done.
Do a little searching. Terminology is important. If you feel that studies and doctors such as Dr. Klotz are in error that is certainly your right. Anecdotal is the wrong terminology. --My friend told me this worked for him --hearsay--and anecdotal.
I don't see any references to study involving men. I see studies involving lines of prostate cancer but that's not the same as actual men with prostate cancer.
Dr. Soren Lehmann of the Cedars-Sinai Medical Center and the UCLA School of Medicine said that “Capsaicin had a profound anti-proliferative effect on human prostate cancer cells in culture. It also dramatically slowed the development of prostate tumours.”
It's a culture study...it's not the same as a human trial....It has interesting and even intriguing effects on pca cells in a culture. Again...the evidence in actual men with prostate cancer is anecdotal (observational using PSA values) unless you have references to actual human trials.
Dr Soren Lehmann, who led the study, said: "Capsaicin had a profound anti-proliferative effect on human prostate cancer cells in culture.
"It also dramatically slowed the development of prostate tumours."
Chris Hiley, head of policy and research at The Prostate Cancer Charity, said: "This is interesting laboratory-based work on cells but we don't yet know how, if at all, it might help men with prostate cancer.
"Eventually, it may be possible to extract the capsaicin and make it available as a drug treatment.
"In the meantime we caution men with prostate cancer in the UK against upping their weekly intake of the hottest known chillies - high intake of hot chillies has been linked with stomach cancers in the populations of India and Mexico.
"For now, if men with prostate cancer want to improve their diet they should avoid fatty foods, eat less red and processed meat, increase their fish intake and enjoy a wide and plentiful range of fruit and vegetables every day."
We are all free to read into these studies what we wish..I take a very conservative and cautious approach and choose to not read more than what these state; more investigation is needed.
Capsaicin is already "extracted" and is easily purchased in capsules the strength of which are noted in hu--heat units.
Human studies? In vivo? This is an older one --a study by one of our guv acronym agencies--paid for with US tax dollars. To read the entire text will cost you $67. I haven't found the synopsis of the study that Dr. Klotz was involved in. I believe that was in 2018. I am rather busy. If you have an interest in capsaicin take a look around. Sometimes a little "clicking" goes a long way. Note the text I placed in bold font. That was the finding of those conducting the study.
Among them, capsaicin, the pungent agent in chili peppers, has been demonstrated to have a role as a tumor suppressor for prostate cancer. Capsaicin potently suppresses the growth of human prostate carcinoma cells in vitro and in vivo. The antiproliferative activity of capsaicin …
I believe you have to pay to access the results in the study above that included 100 men taking a 40,000 hu capsule of Nature's Way capsaicin 2X daily. Yes--Nature's Way found a --way--to extract the capsaicin! The study concluded in 2018. There you go. 100 men with prostate cancer in the study. If you are interested, there is a contact mentioned in the study. Put some time in. None of this is anecdotal.
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