PCa and macular degeneration

[Gearhead]

I suspect I'm not the only one here with Stage 4 PCa and beginning age-related macular degeneration (AMD). Most ophthalmologists recommend that folks with AMD take the AREDS2 supplements, which were shown in NIH trials to slow AMD progression in some cases. FYI, the AREDS2 formula is:

500 mg vitamin C

400 IU vitamin E

10 mg lutein

2 mg zeaxanthin

80 mg zinc

2 mg copper

NIH literature refers to this as a high dose of anti-oxidants.

Finally, here is my question for those of you that know more about supplements than I do. I see warnings that anti-oxidants may be problematic for men with advanced PCa. For example, Tall Allen (replying to a green tea discussion) recently said, "Be careful with antioxidants. Oxidation is how the body rids itself of cancers and precancerous cells, and how the immune system destroys cancer." Should I be taking the AREDS2 formula?

[Tall_Allen]

Tell your oncologist to discuss it with your ophthalmologist.

[Jalbom49]

I have been following Cris Knobbe M.D.

For years. He is on YouTube and has a book on Amazon.

He says some trials with vitamins show no improvement. He also traces the worldwide expansion of AMD to the introduction of processed foods.

Progess of AMD can be slowed or stopped by an ancestral diet.

[LearnAll in reply to Jalbom49]

AND ancestral diet is full of anti oxidants..leaves, roots, seeds ,fruits and so on.

I try to prevent macular degeneration by part of ancient diet called "Saffron" .

[dhccpa in reply to LearnAll]

What is that? Do you mean the spice?

[LearnAll in reply to dhccpa]

Yes..the spice...Saffron. Saffron has carotenoids and other substances which are reported to delay macular degeneration and have some anti cancer effect. For details..see my old post.

healthunlocked.com/advanced....

[dhccpa in reply to LearnAll]

Thanks I'll check it out. I know it's pricey as hell.

[cesces]

For some reason Dr. Myers put me on lef.org's macuguard as a supplement for prostate cancer (and nothing to do with macular degeneration).

Macuguard Is basically

lutein & zeaxanthin

So it appears like it won't hurt.

[Currumpaw in reply to cesces]

Hey cesces!

Dr. Meyers was a trailblazer. You were fortunate to have him. Thanks for the post.

Currumpaw

[Dastardly]

I was diagnosed with AMD years ago - long before I discovered I had Metastatic Pca. I take 1 Macushield capsule daily. The ingredients are:-157mg Marigold extract

10mg Meso-zeaxanthin

10mg Lutein

2mg Zeaxanthin

Does the Macushield work? I can only say that my AMD was in an early stage and has not got any worse. My mother had Glaucoma - I am not taking any chances with my eyesight.

My Onco saw no problems with me taking Macushield, and I cannot say it has had a detrimental effect on me. My PSA was 148 in March 2019 when I was diagnosed with Pca. By June of that year it had reduced to 1.88 by ADT alone. By the time my chemo finished in October 2019, my PSA was undetectable. Since then it has barely increased and is now 0.18.