30 Days on Zytiga - PSA went up

Hello Warriors:

Just got the results back on my first 30 days on Zytiga added to my ADT. The PSA went from 4.6 to 7.8. Does that mean the zytiga does not work?????

Comments appreciated thanks.

[Tall_Allen]

Maybe. 30 days is still pretty new. If still high after another month, maybe have a bone scan/CT.

[Hidden in reply to Tall_Allen]

I had 8 bone mets before starting Abiratone. Scans are up to date with 2 bone mets growing slightly but psa jumped from 1.8 to 4 3 months ago. I thought Abiratone would work quicker??

[LearnAll in reply to Hidden]

This may be what is called "PSA bounce" which means before going down PSA shoots up temporarily...ReCheck PSA after 2 to3 weeks.

And tceinvestment..don;t forget to buy carnival cruiseline (CUK) stock..I got some at $16 a piece.

[Hidden in reply to LearnAll]

Thanks for the info

[LearnAll in reply to Hidden]

I hope it is not "dead cat bounce" .LOL.

[SPEEDYX]

Invest more time in it...my PSA went up for 6 months before it started to come down

[Hidden in reply to SPEEDYX]

Thanks Speedy. What were your numbers???? So appreciate your input

[SPEEDYX in reply to Hidden]

Well I was at a high level 350...came down to 22 then i took zytiga went up to 39 in 6 months and down slowly these past 22 months to 9...everyone is different with treatment

[Hidden in reply to SPEEDYX]

Thanks so much speedy.Wow that is a wonderful decline.

[Hidden in reply to SPEEDYX]

That is a wonderful decline.Do you have any mets?? Are you on lupron or elaguard.

So appreciate your input.

[SPEEDYX in reply to Hidden]

Yes some bone mets and lymph nodes..latest scans are good...was on lupron now switched to eligard

[Hidden in reply to SPEEDYX]

That is really interesting I have bone meds too not too many and only a few are growing. And here I'm freaked out because my PSA hit 7.8 today the highest in my 18-year battle against the beast. You are a great role model for me with all that you've gone through.Thank you You have no idea how much this helps.

[SPEEDYX in reply to Hidden]

I will be praying specifically for you and the need for Zytiga to work!!!

[Hidden in reply to SPEEDYX]

Thank you - God Bless You

[SteveWife in reply to Hidden]

Hi Speedyx, I am saying a prayer for you this evening. And I, too, appreciate this information. My husband is about to start this med. we won’t freak out now if his numbers go up.

[Collarpurple in reply to SteveWife]

Husband has been on abiraterone, lupron shot and prednisone for 17 monthsHe has been very lucky psa went down at every check also medicine has no bothered him. So try not to worry 🙏.

[Hidden in reply to Collarpurple]

Trying not too... Many thanks to all of you. So GREAT to have a reference point here on HealthUnlocked.

[specialmatter]

PSA went up from 11.4 to 64.3 within 2 month after starting Abiraterone+. We were very afraid that it was a failure. But then it dropped down to 3.2 over the time frame of 6 month.

Have patience it might work!

[Hidden in reply to specialmatter]

Oh thanks so much for the info.

[curious-mind1]

It is too early to tell. My dad had the same upward bounce after the first month, and then again after the third month. But the oncologist said, what's important is the overall movement over three months to be downward.

Art

[Hidden in reply to curious-mind1]

Thanks so much Art. Encouraging

[ForJoel]

My husband started Zytiga in Dec 2018. His PSA went up for three months, plateaued at 7, and then it slowly began to come down. It goes down a little every test, and he is now at .6.

[Hidden in reply to ForJoel]

Oh that is good news. Thanks for the input

[Pmann]

This is all really good info as i begin abiraterone in just a few days after two years with Erleada. Had to kick her to the curb. She did a good job though. Sure not looking forward to the Prednisone but you just have to take what comes your way.

[Hidden in reply to Pmann]

Actually - no side effects from the Prednisone. I just take 5 mg a day with the Zytiga. Take a water pill for fluid retention.Good luck...

[Pmann]

i am already on chlorthalidone ? for the same thing with Erleada.

[PlantHero]

No, it doesn’t...just like a PSA check following a biopsy - PSA’s explode - which actually mean that it’s stirring things up, it’s working; next will be the hot-flashes, which means the same thing - “it’s working!”

[Hidden in reply to PlantHero]

Thanks so much. I hope so.

[j-o-h-n]

We all are worryworts........

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 12/03/2020 5:11 PM EST

[Hidden in reply to j-o-h-n]

That we are John.Thanks so much.

[Collarpurple in reply to j-o-h-n]

Very true. Try to just live life and then it’s test time and reality hit you damn😡