Looking for help in controlling nausea and vomiting. For the last 12 months I pretty much have experienced nausea daily with vomiting several times per week. I have a complete GI work up with nothing out of the ordinary , Brain scan also clean, so we’re thinking one of the drugs but how to find out which one. I’ve using Zofran with limited success.
At this time I’m on 75 mg of morphine twice a day
Xtandi
Veneflaxine
Then have Lupron, and Zometa injections every three months.
I am not an expert on these things but when a psma scan done a couple of weeks ago, it showed that I have LN Mets in the abdomen and pelvic. The MO who managed the psma trial told me if you do radiation, it will give you the symptoms you described, nausea and vomiting. So, I am not sure if this is related to the radiation you did or not. Just a thought.
Does cannabis help?
Cannabis does help if I can get ahead of it, but does help during the day. Some time I wake up to projectile vomiting which is a rough way to start the day.
When feel sick to my stomach marijuana seems to help immensely.
Like others said, cannabis may help considerably.
I’m not saying this is the reason ..... but 150mg of morphine daily is a considerable. Many people that take less might get nauseous and even throw up a little as a daily consequence of the opiates. as a course of events , they might even get used to looking forward to that nausea in perspective. if you have been taking those twin 75s for a while , you have to keep an eye on taking them on time regularly. If you miss a dose , nausea will soon follow. Then .... then .... after you have been taking that much long enough , the opiate receptors in your brain will grow to want more ... it’s called “ tolerance “ ... when tolerance builds up enough the amount you are taking will no longer seem to do much of anything and you will start to experience “ tolerance withdrawal “ automatically. At which time you will start to get dope sick , nausea, and in some people vomiting. If this is the case for you .... every time this happens you have to “ clean up “ and stop the meds for a few weeks ( pain or not , cannabis helps here ) to kill off the dope sickness and re-potentiate the morphine. The longer you take 150 daily, the more often you have to do this. Of course the alternative is just to take more until your brain receptors are happy. “ this “ is both a really bad and potentially dangerous idea and you should never try that. I don’t know if this is your problem but it does fit the symptoms.
Just say’in 💪💪💪💪👍👍👍🦋🌵🌸🌼🌈❤️
I’ve only started the morphine in the last several months, where I’ve been battling this for close to 12 months. I know I meet with my palliative care specialist to avoid addiction problems.
Thanks for the thoughts.
Roger that .... there is a significant difference between physical tolerance and mental addiction in opiate use. The tolerance is naturally caused by the brain building more opiate receptors causing someone to experience the unpleasant effects of withdrawal. Addiction is when a person becomes mentally dependent on the drugs effects and cannot quit. Addiction is the bad one because it’s most difficult to treat. Basically , if you can quit any time you want and stay off without issues , you are not addicted. Often addiction and withdrawal go hand and hand. Everyone that takes opiates for an extended period of time will experience withdrawal... withdrawal can be very nasty in many people. In people that experience extremely unpleasant effects caused by withdrawal, there are numerous ways to minimize the problems. Addiction and tolerance is a big subject , too big to address here . Normally the higher the dose of opiates you take for extended periods, the greater the negative effects of withdrawal. Your medical team will know how to wean you off opiates if it ever becomes necessary. Most all of us are in palliative care and opiate tolerance really isn’t an issue. We are going to need pain management until the end.
Peace brother 💪💪💪💪👍👍👍
Talk with you MO about drugs based in cannabis, and approved by the FDA for nausea etc in patients with cancer.
Jack,
When my wife was on Velcade for multiple myeloma, she was prescribed Ondansetron [Zofran] for nausea. It was very effective. She rarely needs it with her current chemo (Revlimid) but renewed her prescription yesterday - 84 cents for 20 4 mg tablets.
-Patrick
Jack,
sorry to hear about the nausea and throwing up ... I was just reading a newly approved drug that likley will replace Lupron -- it is oral -- maybe you could ask to be switched to it.
Relumina better that leuprolide in HERO trial
candied ginger root is both safe and effective
Hi Jackpine,
All my family don't tolerate morphine, even 3mg a day. We start vomiting 8 or 10 times several hours after talking it.
But we tolerate very well opium, even 25mg 4 times in 24 hours. Maybe more? It's really different from one person to another.
We wish you all the best ! Claud
I keep thinks “some” food is a good thing. Crackers, small pancakes in the AM, anything to add bulk to the GI track.
It’s the morphine. That’s a big dose. No other options do pain?
Hi Jackpine,
If essential oils appeal to you as an adjunctive path, you might consider having some peppermint essential oil around to inhale. It has anti-nausea and anti-spasmodic properties. I would use it by just un-capping and sniffing/inhaling (most small bottles come with a dropper cap that will protect the oil but allow you to get the scent.) A diluted topical application would be another possibility, but the inhale technique is super quick and easy. A 5 ml bottle should last 1-2 years. Feel free to ask me if you have any questions (disclosure: I do not sell oils. I just enjoy them and have used them as adjunctive therapy for years, including to help provide pain relief and comfort for my Dad).
Also, I'm so sorry you have to go through this. Sending prayers, good energy and a big HUG your way!
In solidarity,
-Sunlight
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