Next steps with high PSA during Jevtana

[tomtom9148]

Hi folks,

I have had 3 infusions of Cabazitaxel over the past 10 weeks and I am due to go in tomorrow (Thursday, 8/27). My PSA has been rising dramatically, from 5.7 on 4/20 to 32.24 today. My scans did not show any decrease in Mets (S2, L2, T4,5,6,7), and a slight "shadow" of increase. My doc and I agreed to take Xtandi again for 2 months or so to see if it can attack the PSA again, then to consider Xofigo radiation to attack the bones. Do you folks have any suggestions? I was diagnosed in May of 2016 and have been pretty aggressive in my treatments: Docetaxel, Lupron, Xtandi, clinical trials at NIH and Sarah Cannon, so I am willing to do the next right thing.

Thanks, Tom

[Tall_Allen]

Xofigo seems to combine well with Provenge.

Can you get a biopsy of the resistant metastases?

[Hidden]

That’s the spirit Tom Tom ! There is much hope in trials! I Hope that you will be able to get that PSA down and eliminate the pc this time for good! Keep hitting it ! 🥊

[tomtom9148 in reply to Hidden]

Thanks Whimpy, one day at a time

[Hidden in reply to tomtom9148]

I Say “ one day at a time sweet Jesus” being a Christian ..... I pray for mercy .. It never ceases to amaze me how much a man can take with reasons to live . Hang in there .🙏💪