Put another way: Tumor growth can be a byproduct of cancer treatments that kill tumor cells.

[Claud68]

New Principle for Eradicating Cancer: Leave No Dead Cells Behind;

isbscience.org/news/2017/11...

This is an interesting option. Do you think that low-dose Aspirin (25mg?) could really do the job?

[tango65]

Very interesting, Thanks for posting.

Best of luck!!

[AlanMeyer]

Interesting idea. It would seem to be a cheap, well tolerated treatment. I think the usual dose of aspirin for heart patients is 81 mg, about 1/4th the standard size 325 mg aspirin.

Alan

[Claud68 in reply to AlanMeyer]

Thanks for your reply, Alan. It seems to be a very low quantity. I wonder if it is enough to produce the needed Resolvins?

[AlanMeyer in reply to Claud68]

I wonder about that myself. Why, if it's okay to take up to 12 aspirin tablets in a day, do we only prescribe 1/4 of one tablet per day for people with heart disease? The idea is to avoid stomach ulcers but aren't cancer or heart attack bigger risks?

Sometimes as little as a single study, and not always one with iron clad design (how many of them are like that?) determines recommendations followed by tens of millions of people.

I believe that a hundred years from now people will look back at our era and shake their heads at the primitive state of medicine in our time. But, well, we're certainly better off than we were 100 years ago when there were no cancer treatments at all.

Alan

[Hidden]

Claud68,

Just curious to know your status and treatment history if you don't mind sharing that.

[noahware]

In the article: "This phenomenon of cancer drugs as a double-edged sword may be considered discouraging. (Will cancer drugs then ever work?) "

I think what this may point to, especially as regards slow-growing PC, is that we might better concern ourselves with keeping the growth slow and asymptomatic rather than attempting (in futility?) a total destruction of all cancer cells.

I am happy to die WITH my cancer, so long as it leaves me relatively healthy and free of pain. If I fight my cancer TOO hard, might I be more likely to die OF it rather than merely with it?

[Claud68]

One of the conclusion IMO after reading this article could be that surgical removal of a whole cancer tumor or even of several mets if it's possible, is a very better choice than RT or chemotherapy !?

[George71]

Thanks for posting. CBD and Celebrex may have similar anti-Inflammatory effects.

[MateoBeach]

Interesting indeed. Here is some more on the science of aspirin - resolvins - cancer connection. Noting that there is also the counter mechanism of the abscopal response: That cellular "debris" from chemo or RT killed cancer cells causes an immune response that goes after surviving cancer cells in the body. I do not know enough whether aspirin will produce the desired resolvin mediated anti-inflammatory mechanisms (including macrophage activation) while still permitting the up-regulation of T-call mediated abscopal response.

But it is pertinent to my upcoming treatment with Veyonda and Lu-PSMA in Australia. (As per the DARRT and LuPIN trials referenced previously.)

ncbi.nlm.nih.gov/pubmed/291...

ncbi.nlm.nih.gov/pubmed/308...

[AlanLawrenson in reply to MateoBeach]

When do you start Veyonda? are you doing it in the LuPin trial at St Vincent's?

[MateoBeach in reply to AlanLawrenson]

Outside of the trials on a compassionate basis and must pay for it of course. Fortunately supported and supervised by my RT in Oz who will be doing the Lu-PSMA used with it. Similar

Protocol to the LuPIN trial.

[Bigblock]

Hmm I apologise that I tend to lean towards the alternative side of health care since I was diagnosed 4 years ago, and I find it strange that I knew this 4 years ago as it’s common knowledge, I agree that surgery may be the best option, but there’s no guarantee with that either, it appears a lot of the damage could come from the biopsies where they spread Tumor stem cells around the body, and the trouble with radiation and chemo is they may get the bulk of it but they don’t get it all and what’s left eventually becomes more aggressive as it says in the article, they should have been looking at this years and years ago if they want an effective treatment plan in imo

[j-o-h-n]

I still think Chocolate Chip ice cream (two scoops) is the answer....

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 03/02/2020 5:02 PM EST

[tallguy2]

Thanks for posting this. I stopped my low-dose aspirin a year ago. Perhaps time to restart?

[immunity1]

interesting articles and good to be reminded of such anti-inflammatory effects. Whatever the reasons: inhibition of blood supply to tumour or re-population of tumour cells or direct cytokine inhibition. Clearly more epidemiological data on low dose aspirin because of its global use for CV disease but I like the idea of celecoxib, especially when undergoing docetaxel Rx where platelets are being hammered (bleeding issues). =R

[GeorgeGlass]

Here is a study with a 40mg option: pubmed.ncbi.nlm.nih.gov/111....

Good article, I was thinking this before I got my primary treatments, and what he focused on in the article, is exactly what happened to me.