Targeting a single enzyme can kill prostate cancer cells

[GeorgeGlass]

news-medical.net/amp/news/2...

For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme, called PI5P4Kα. The findings, published recently in Science Advances, could help address the growing threat of treatment resistance in prostate cancer and could also lead to improved treatments for other cancers, such as those affecting the breast, skin, and pancreas.

[Rolphs]

Another promising avenue for research. Appreciate the post!😃

[Jbooml]

hi George, should have known you’d be first to post this. Not sure when we’ll see a trial but it might just coincide with my predicted CR timeline. How you been doing.

[GeorgeGlass in reply to Jbooml]

been busy helping my mom. Been neglecting my own health and medical needs. Psa is low but the cancer has moved a little. Orgovyx does nothing now, but nubeqa is working for now. How about you?

[Jbooml in reply to GeorgeGlass]

Been well wrt to the beast..lost my wife last year to breast cancer. So glad you’re still kicking. I’ve been a little out of touch on the message board. People ask me stuff once in a while especially Zytiga..I quit 2 years ago but no advancement so far…tell me if you find something good..appreciate the belated response. Still take the dukarol biannually as my kicker to the ADT.

Thanks Jeff

[Benkaymel]

Wow, very promising!. Let's hope a trial is available when I become CR whenever that may be.

[MarkEmrys]

interesting that University of Bern issued a press release about this in 2020…

[6357axbz in reply to MarkEmrys]

I guess not much progress since then

[MarkEmrys in reply to 6357axbz]

hard to know — could not find anything about clinical trials

[Dban]

another article that delves deeper. science.org/doi/10.1126/sci...

[lithocam]

Wow! That's interesting and hopeful news.

[awb1]

The details in the articles fly over my head, but seeing the word lipid many times (fats), I wonder if there is a connection between these reports and the idea that a statin contributes to the control of PCA. I take a low dose of rosuvastatin to drive my cholesterol and lipids to very healthy levels. The devil is always in taking and applying findings out of a petri dish. Wondering when TallAllen will contribute to this thread.

[6357axbz in reply to awb1]

the latest statin study recently reported here by pjoshea said rosuvastatin didnt help but simvastatin did

[GeorgeGlass in reply to 6357axbz]

Do you have that study? I can’t handle simvastatin.

[awb1]

Hi, thanks, but did you mean to provide a link to that statin study?

[6357axbz in reply to awb1]

I didn’t but looked it up for you anyway

healthunlocked.com/redirect...

[Bspouse]

Thank you for this information - and so grateful to the scientists who keep looking for breakthroughs in this evil disease.

[Nfler in reply to Bspouse]

But nothing new since, ugh

[Nfler]

It’s2024 and nothing new since, ugh

[GeorgeGlass in reply to Nfler]

Typical. Must be no money in it for big pharma.