New signs of cancer in my L3 vertebrate

[Teambaratta]

My diagnosis was prostate cancer Gleason 9.6

Had prostecamy and 28 lympnodes removed in pelvic area on Nov 2016 .. no signs of cancer till now . Had radiation 6 wks in 2018 june

Hello group it's been awhile since iv been on the site . But I hit a problem my prostate cancer has spread to my L3 vertebrate about 1.3 cm now and my doc has suggested DOCETAXEL 80 MG or a clinical trial called ENZALUTAMIDE W/ or/wo RADIUM 223 DICHLORIDE. I'd like to know if anyone has had these meds and what the outcome has been good or bad .. thank you for your time .

[Hidden]

Sorry about the L-3 ... do you have pain there? I hope not... but now you’ve got to throw another round at it.. keep the team together Baratta ... 😎

[Tall_Allen]

Both good choices. I believe the enzalutamide trial also includes a bone-preserving agent which seems to be necessary when combining it with Xofigo.

[Schwah]

Have you considered SBRT radiation to your one lesion ? If it’s relatively safe to get to, why not? I would never recommend doing that in lieu of systematic treatment but rather in addition to. Some early studies are indicating it might help.

Schwah

[pjoshea13]

You seem to have oligometastatic disease, which means that treating the lesion is an option - without the morbidity osf systemic treatments (which are not cures anyway.)

I had L5 zapped 5 years ago. I don't regret it at all. But I'm not your doctor & you should discuss this with one who is up on oligometastatic treatment.

Best, -Patrick

[joeguy]

I do not have any bone mets (that we know of), just lymph nodes, but Xtandi (Enzalutamide) has worked amazingly well for me. PSA has been undetecable for about a year.

[Teambaratta]

Thanks everyone for your input I'll be discussing my options today with my doc but I'm leaning to chemo ( docetaxel ) because it's most likely to work in my case instead of a clinical trial where I'll be to a split group study and not definitely which group I'll be in ...